PMID: 20640999Jul 20, 2010Paper

Quality of Vision Index: a new method to appraise visual function changes in age-related macular degeneration

European Journal of Ophthalmology
Stefano PiermarocchiGianni Virgili

Abstract

To explore the correlation between psychophysical measures of visual function and vision-related quality of life (QOL) in exudative age-related macular degeneration (AMD) and to obtain a new quality of vision index expressed as corrected visual acuity (cVA) that is scaled like visual acuity (VA), but that incorporates the weighted contribution of VA, contrast sensitivity (CS), and reading ability. Visual acuity, CS, and reading ability were measured in 293 patients with AMD in this multicenter prospective study. Vision-related QOL was quantified by the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). The validity of the questionnaire was assessed using Rasch analysis. The relationship between psychophysical tests and NEI-VFQ-25 scores was investigated. A cVA index was developed integrating Rasch-scaled NEI-VFQ-25 score with VA, CS, and reading ability as a tool to be used for evaluating vision-related QOL on the same scale as VA. A total of 27.5% of the variability of VFQ score was found to be explained by VA alone in patients with AMD. The proportion of Rasch-scaled QOL estimate variance explained by cVA was 33.2% as compared to 27.5% explained by VA and 24.5% by CS, which was a statistically signific...Continue Reading

References

Oct 1, 1992·Journal of the American Geriatrics Society·M S MarxR Feldman
Feb 11, 1991·Archives of Ophthalmology·R J GlynnE W Campion
Mar 1, 1991·Journal of General Internal Medicine·R F UhlmannL G Duckert
Dec 29, 1988·The New England Journal of Medicine·M E TinettiS F Ginter
Jan 1, 1988·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·J E Lovie-Kitchin
Feb 1, 1981·Acta Ophthalmologica·P Bernth-Petersen
Apr 1, 1981·Acta Ophthalmologica·P Bernth-Petersen
Mar 23, 1995·The New England Journal of Medicine·S R CummingsT M Vogt
Aug 1, 1994·The British Journal of Ophthalmology·M LundströmA Sjöblom
Mar 1, 1994·Archives of Ophthalmology·I U ScottM F Folstein
May 1, 1994·Archives of Ophthalmology·E P SteinbergA M Damiano
Apr 1, 1993·Journal of the American Geriatrics Society·C CarabelleseM Trabucchi
Sep 11, 1999·American Journal of Ophthalmology·C M MangioneJ M Seddon
Feb 24, 2000·The British Journal of Ophthalmology·M E McClureU Chakravarthy
Jun 27, 2001·Survey of Ophthalmology·R W Massof, G S Rubin
Jun 26, 2003·Investigative Ophthalmology & Visual Science·Konrad PesudovsDavid B Elliott
Jul 2, 2004·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Michiel R de BoerGer H M B van Rens
Sep 29, 2004·Investigative Ophthalmology & Visual Science·Gianni VirgiliUNKNOWN MNREAD charts
Jun 16, 2006·BMC Ophthalmology·Konrad Pesudovs
Dec 28, 2006·European Journal of Ophthalmology·S PiermarocchiM Varano

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.