Quality specifications for the determination of copper, zinc, and selenium in human serum or plasma: evaluation of an approach based on biological and analytical variation

Clinical Chemistry
Josiane ArnaudAndrew Taylor

Abstract

Trace element external quality assessment schemes monitor laboratory performance and provide a stimulus for improvement in accuracy. However, monitoring of participant performance varies according to the scheme and can lead to conflicting conclusions. Quality specifications based on biological intra- and interindividual variability were calculated and compared to those currently used by various trace element external quality assessment schemes for plasma or serum copper, zinc, and selenium concentrations. For this purpose, we evaluated results reported by participating laboratories in different schemes, at key concentrations, using z scores. Minimal quality specifications developed from the biological intra- and interindividual variability were, for Cu, +/-0.84 micromol/L or 12% of the assigned target concentration, whichever is greater; for Zn, +/-1.20 micromol/L or 15% of the assigned target concentration, whichever is greater; and for Se, +/-0.072 micromol/L or 12% of the assigned target concentration, whichever is greater. Reported performance of the participating laboratories depended on analyte, concentration, and the selected quality specification. In addition, the most commonly used methods for the determination of Cu, ...Continue Reading

References

Nov 1, 1990·The Journal of Nutrition·J C King
Nov 1, 1996·Annals of Clinical Biochemistry·A Taylor
May 20, 1998·The American Journal of Clinical Nutrition·A Cordano
May 20, 1998·The American Journal of Clinical Nutrition·D Beshgetoor, M Hambidge
Feb 10, 2000·Scandinavian Journal of Clinical and Laboratory Investigation·C G Fraser
Feb 10, 2000·Scandinavian Journal of Clinical and Laboratory Investigation·C RicósM Simón
Oct 31, 2001·Public Health Nutrition·K M Brown, J R Arthur
May 6, 2003·The Journal of Nutrition·Hoon Shim, Z Leah Harris
Sep 26, 2003·Journal of Pediatric Gastroenterology and Nutrition·Magdalena ArayaRicardo Uauy
Feb 27, 2004·European Journal of Clinical Nutrition·C D Thomson
Mar 25, 2005·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Kerry E KilpatrickLynn Whitener
Sep 28, 2005·Archives of Toxicology·M StefanidouC Spiliopoulou
Dec 28, 2006·Journal of the American Academy of Dermatology·Emanual MaverakisNasim Fazel
Apr 25, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Bonnie Ransom SternTom Starr
Apr 9, 2008·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Maria G Boosalis

❮ Previous
Next ❯

Citations

May 28, 2010·The Journal of Biological Chemistry·Henry R MaunSarah G Hymowitz
Dec 15, 2010·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Andrew Taylor
May 7, 2014·Toxicology Mechanisms and Methods·Alain PineauElizabeth Françoise-Burg
Sep 7, 2016·Laboratory Medicine·F Bernhard KrausBeatrice Ludwig-Kraus
Oct 19, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Benoit Chovelon, Josiane Arnaud
May 14, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Meredith L PraamsmaUNKNOWN Network of Organisers of External Quality Assurance Schemes in Occupational and Environmental Laboratory Medicine
Feb 12, 2017·Journal of Clinical Laboratory Analysis·Frank Bernhard Kraus, Beatrice Ludwig-Kraus
Jul 2, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Mandy LegerBenoit Chovelon
Dec 8, 2019·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Josiane ArnaudCas Weykamp

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.