PMID: 8589042Oct 1, 1995Paper

Quantification and molecular analysis of plasmatic HLA-BCw molecules with a locus B and Cw HLA specific mAb (B1.23.2 mAb)

European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics
M DrouetR Fauchet

Abstract

Plasmatic HLA class I molecules were analysed quantitatively and qualitatively with a B and Cw locus-specific mAb, B1.23.2. sHLA-BCw were detected among all individuals with a wide range of concentration. The HLA-A29(19) allele was significantly associated with an increased sHLA-BCw mean concentration. Three different isoforms of relative molecular weights of 44, 39 and 36kDa were detected. The 39 kDa class I heavy chain was not detected after immunoprecipitation with mAb B1.23.2 in 17% of tested plasma, but was immunoprecipitated with W6/32 mAb.

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Citations

Apr 20, 2001·Mechanisms of Ageing and Development·C Le MorvanM Drouet
Dec 23, 1998·Mechanisms of Ageing and Development·C Le MorvanM Drouet
Nov 15, 2002·Molecular Immunology·Carla A HerbertsCécile A C M van Els
May 22, 2018·The Journal of Clinical Investigation·Marco CardoneMichael A Norcross
Apr 28, 2005·International Journal of Cancer. Journal International Du Cancer·Annette PaschenDirk Schadendorf
Nov 25, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·John SidneyAlessandro Sette

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