PMID: 9649952Jul 3, 1998Paper

Quantification of apolipoprotein AI-containing lipoprotein particles in non-insulin-dependent diabetes mellitus

Diabetes Research and Clinical Practice
E ContieroM Folin

Abstract

Quantification of LpAI (lipoprotein particles containing apolipoprotein AI not associated with apolipoprotein AII) was performed through an electroimmunoassay on serum from 49 non-insulin-dependent diabetic patients (mean age 60 +/- 9 years) and 53 age-matched control subjects of both sexes not affected by coronary heart disease. Serum lipid and lipoprotein levels were not significantly different between the two groups. Serum levels of LpAI determined for diabetic patients did not differ from those of control subjects, while concentrations of LpAI in men were significantly lower than in women, both among diabetics (P < 0.05) and controls (P < 0.005). Serum levels of apolipoprotein AI and high density lipoprotein cholesterol were significantly correlated with those of LpAI (P < 0.005, for both variables). On the contrary, levels of LpAI/AII (lipoprotein particles containing both apolipoprotein AI and AII) were significantly increased in diabetic patients (P < 0.005).

References

Jun 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·H J ParraG Luc
Jun 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·E L Bierman
Dec 1, 1991·Metabolism: Clinical and Experimental·G LucJ Davignon
Oct 1, 1990·Acta diabetologica latina·C M BarbagalloA Notarbartolo
Jan 1, 1989·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·T OhtaI Matsuda
Jan 15, 1987·Biochemical and Biophysical Research Communications·R BarbarasG Ailhaud
May 1, 1986·Mayo Clinic Proceedings·B A KottkeS J Mao
Jan 1, 1986·Methods in Enzymology·M C Cheung
Feb 1, 1994·Mayo Clinic Proceedings·A RastogiB A Kottke
Jan 1, 1993·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·R W Stout

❮ Previous
Next ❯

Citations

Feb 10, 2004·Metabolism: Clinical and Experimental·Trisha A KurtzMark A Deeg
Nov 27, 2001·Critical Reviews in Clinical Laboratory Sciences·J FrohlichK W Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.