Quantification of arterial flow using digital subtraction angiography

Medical Physics
O BonnefousD Ruijters

Abstract

In this paper, a method for the estimation of arterial hemodynamic flow from x-ray video densitometry data is proposed and validated using an in vitro setup. The method is based on the acquisition of three-dimensional rotational angiography and digital subtraction angiography sequences. A modest contrast injection rate (between 1 and 4 ml/s) leads to a contrast density that is modulated by the cardiac cycle, which can be measured in the x-ray signal. An optical flow based approach is used to estimate the blood flow velocities from the cyclic phases in the x-ray signal. The authors have validated this method in vitro, and present three clinical cases. The in vitro experiments compared the x-ray video densitometry results with the gold standard delivered by a flow meter. Linear correlation analysis and regression fitting showed that the ideal slope of 1 and intercept of 0 were contained within the 95 percentile confidence interval. The results show that a frame rate higher than 50 Hz allows measuring flows in the range of 2 ml/s to 6 ml/s within an accuracy of 5%. The in vitro and clinical results indicate that it is feasible to estimate blood flow in routine interventional procedures. The availability of an x-ray based method fo...Continue Reading

References

Jan 1, 1981·The Proceedings of the Nutrition Society·A J Webster
Jan 1, 1996·Ultrasound in Medicine & Biology·C K HollandT R McCauley
Jul 1, 1992·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P N Burns
Apr 13, 2005·IEEE Transactions on Medical Imaging·Kawal S RhodeAlexander M Seifalian
Aug 14, 2008·Medical Physics·Irina WaechterDavid J Hawkes
Jun 3, 2009·Journal of Neuroradiology. Journal De Neuroradiologie·L AugsburgerDaniel Rüfenacht
Sep 29, 2009·Annual Review of Fluid Mechanics·Daniel M SforzaJ R Cebral
Dec 10, 2009·Medical Physics·Baruch B LieberLiliana Cesar
Oct 29, 2010·Medical Engineering & Physics·G MulderF N van de Vosse
Nov 29, 2011·International Journal of Vascular Medicine·Xavier ArmoiryFrancis Turjman
May 1, 2012·Journal of Neurointerventional Surgery·Emanuela CrobedduH J Cloft

Citations

Mar 28, 2016·International Journal of Computer Assisted Radiology and Surgery·Marco BoegelMarkus Kowarschik
Jul 9, 2013·Computer Methods and Programs in Biomedicine·Tung-Hsin WuTzung-Chi Huang
Jan 26, 2013·European Journal of Radiology·Vitor M PereiraLovblad Karl-Olof
Feb 2, 2015·Journal of Biomechanics·H G Morales, O Bonnefous
Sep 17, 2016·AJNR. American Journal of Neuroradiology·H G MoralesI Larrabide
Apr 8, 2017·AJNR. American Journal of Neuroradiology·J R CebralD Ruijters
Jun 13, 2017·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Liang-Der Jou
Jan 18, 2014·Stroke; a Journal of Cerebral Circulation·Ajay K WakhlooL Pierot
Apr 19, 2017·Journal of Biomechanical Engineering·Zifeng YangBryan Ludwig
Dec 25, 2015·Journal of Neurointerventional Surgery·Marta Aguilar PérezV M Pereira
Nov 18, 2018·Journal of Magnetic Resonance Imaging : JMRI·Baohong WenBing Wu
May 3, 2019·Applied Optics·Zifeng Yang, Mark Johnson
Apr 23, 2020·Journal of Neurointerventional Surgery·Nicole Mariantonia CancelliereVitor M Pereira
Nov 26, 2020·Journal of Magnetic Resonance Imaging : JMRI·Sung Won Youn, Jongmin Lee
Apr 7, 2016·Topics in Magnetic Resonance Imaging : TMRI·V M PereiraMaria Isabel Vargas

Related Concepts

Arteries
Carotid Arteries
Structure of Cerebral Artery
Hemodynamics
Angiography, Digital Subtraction
Radiologic Phantoms
Angiogram
Angiography, Digital Subtraction
Densitometry, X-Ray
Gold

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.