Quantification of Axial Abnormality Due to Cerebellar Ataxia with Inertial Measurements

Sensors
Nhan NguyenDavid Szmulewicz

Abstract

Cerebellar Ataxia (CA) leads to deficiencies in muscle movement and lack of coordination that is often manifested as gait and balance disabilities. Conventional CA clinical assessments are subjective, cumbersome and provide less insight into the functional capabilities of patients. This cross-sectional study investigates the use of wearable inertial sensors strategically positioned on the front-chest and upper-back locations during the Romberg and Trunk tests for objective assessment of human postural balance due to CA. The primary aim of this paper is to quantify the performance of postural stability of 34 patients diagnosed with CA and 22 healthy subjects as controls. Several forms of entropy descriptions were considered to uncover characteristics of movements intrinsic to CA. Indeed, correlation with clinical observation is vital in ascertaining the validity of the inertial measurements in addition to capturing unique features of movements not typically observed by the practicing clinician. Both of these aspects form an integral part of the underlying objective assessment scheme. Uncertainty in the velocity contained a significant level of information with respect to truncal instability and, based on an extensive clustering ...Continue Reading

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Citations

Feb 14, 2020·Sensors·Tanjila Akter ZilaniXiaodong Yang
Sep 25, 2019·Sensors·Marco GhislieriValentina Agostini
Jun 13, 2020·Scientific Reports·Bipasha KashyapDavid Szmulewicz
Dec 6, 2020·Journal of Neuroengineering and Rehabilitation·Ha TranDavid J Szmulewicz
Mar 5, 2021·Current Neurology and Neuroscience Reports·Jamie L AdamsRuth B Schneider

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Software Mentioned

MATLAB
ApEn
SampEn
FuzzyEn

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