Quantification of coronary plaque by 64-slice computed tomography: a comparison with quantitative intracoronary ultrasound

Investigative Radiology
Masato OtsukaPim J De Feyter

Abstract

Noninvasive assessment of coronary atherosclerotic plaque may be useful for risk stratification and treatment of atherosclerosis. We studied 47 patients to investigate the accuracy of coronary plaque volume measurement acquired with 64-slice multislice computed tomography (MSCT), using newly developed quantification software, when compared with quantitative intracoronary ultrasound (QCU). Quantitative MSCT coronary angiography (QMSCT-CA) was performed to determine plaque volume for a matched region of interest (regional plaque burden) and in significant plaque defined as a plaque with > or =50% area obstruction in QCU, and compared with QCU. Dataset with image blurring and heavy calcification were excluded from analysis. In 100 comparable regions of interest, regional plaque burden was highly correlated (coefficient r = 0.96; P < 0.001) between QCU and QMSCT-CA, but QMSCT-CA overestimated the plaque burden by a mean difference of 7 +/- 33 mm3 (P = 0.03). In 76 significant plaques detected within the regions of interest, plaque volume determined by QMSCT-CA was highly correlated (r = 0.98; P < 0.001) with a slight underestimation of 2 +/- 17 mm3 (P = not significant) when compared with QCU. Calcified and mixed plaque volume was ...Continue Reading

References

Apr 16, 1998·Catheterization and Cardiovascular Diagnosis·N BruiningJ R Roelandt
Apr 13, 2001·Journal of the American College of Cardiology·S SchroederK R Karsch
Sep 18, 2001·Lancet·K NiemanP J de Feyter
Dec 30, 2003·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Sebastiaan A De WinterNico Bruining
Mar 5, 2004·JAMA : the Journal of the American Medical Association·Steven E NissenUNKNOWN REVERSAL Investigators
Apr 14, 2004·Circulation·Sabine PankuweitBernhard Maisch
Jul 31, 2004·American Journal of Public Health·Gary A Giovino
Apr 21, 2005·European Heart Journal·Sebastian LeschkaSimon Wildermuth
May 10, 2005·The American Journal of Cardiology·Nico R MolletPim J de Feyter
Aug 2, 2005·Journal of the American College of Cardiology·Gilbert L RaffJames A Goldstein
Dec 13, 2005·European Radiology·Thomas G FlohrBernd M Ohnesorge
Mar 15, 2006·JAMA : the Journal of the American Medical Association·Steven E NissenUNKNOWN ASTEROID Investigators
Jun 24, 2006·AJR. American Journal of Roentgenology·Konstantin NikolaouChristoph R Becker
Sep 12, 2006·European Journal of Public Health·Johan P Mackenbach
Jan 16, 2007·Investigative Radiology·Marc DeweyBernd Hamm
Feb 9, 2007·Investigative Radiology·Anja J ReimannMartin Heuschmid
Apr 12, 2007·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nico BruiningRonald Hamers
Aug 21, 2007·Journal of the American College of Cardiology·Annick C WeustinkPim J de Feyter

❮ Previous
Next ❯

Citations

May 21, 2010·European Heart Journal·Stephan Achenbach, Paolo Raggi
Oct 29, 2009·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Tobias SaamKonstantin Nikolaou
Jan 25, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Hyuk-Jae Chang, Namsik Chung
May 3, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Sei KomatsuKazuhisa Kodama
May 15, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Patrick W SerruysYoshinobu Onuma
Aug 24, 2011·World Journal of Cardiology·Faisal SharifWilliam Wijns
Mar 19, 2014·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Björn A BlombergPoul F Høilund-Carlsen
Sep 21, 2013·The International Journal of Cardiovascular Imaging·Richard A P TakxTim Leiner
May 31, 2014·The British Journal of Radiology·L BousselP Douek
Mar 26, 2013·Current Cardiovascular Imaging Reports·Alan C KwanDavid A Bluemke
Mar 29, 2011·Current Problems in Diagnostic Radiology·Eugene LinWayne Hwang
Jun 5, 2010·Journal of the American College of Radiology : JACR·Eugene Lin
Oct 13, 2009·Journal of Cardiovascular Computed Tomography·Srikanth Sola, Milind Y Desai
May 13, 2009·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Carole J DennieUNKNOWN Canadian Association of Radiologists
Aug 12, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Faisal Sharif, Ross T Murphy
Jul 3, 2015·The International Journal of Cardiovascular Imaging·Arthur NasisSujith K Seneviratne
Jul 15, 2015·Journal of Cardiovascular Computed Tomography·Annika SchuhbaeckDamini Dey
Feb 26, 2011·JACC. Cardiovascular Interventions·Gabriel VorobiofJagat Narula
Nov 17, 2009·Archives of Cardiovascular Diseases·Dominique BoulmierHervé Le Breton
Feb 17, 2015·BioMed Research International·Lei XuZhanming Fan
Aug 16, 2016·The International Journal of Cardiovascular Imaging·Kohichiro Iwasaki, Takeshi Matsumoto
Apr 12, 2014·Arteriosclerosis, Thrombosis, and Vascular Biology·Dan K KalraJames K Min
Feb 20, 2016·Circulation Research·Jason M TarkinJames H F Rudd
Jul 15, 2015·Circulation. Cardiovascular Imaging·Veit SandfortDavid A Bluemke

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.