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Quantification of GC-biased gene conversion in the human genome

bioRxiv

Oct 9, 2014

Sylvain GléminLaurent Duret

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Abstract

Many lines of evidence indicate GC-biased gene conversion (gBGC) has a major impact on the evolution of mammalian genomes. However, up to now, this process had not been properly quantified. In principle, the strength of gBGC can be measured from the analysis of derived allele frequency ...read more

Mentioned in this Paper

Gene Polymorphism
Simulation
Genetic Polymorphism
Mutation Abnormality
Population Group
Genome
Patterns
Genetic Hotspot
CpG Islands
Genome-Wide Association Study
11
1
Paper Details
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  • Quantification of GC-biased gene conversion in the human genome

    bioRxiv

    Oct 9, 2014

    Sylvain GléminLaurent Duret

    PMID: 990010173

    DOI: 10.1101/010173

    Abstract

    Many lines of evidence indicate GC-biased gene conversion (gBGC) has a major impact on the evolution of mammalian genomes. However, up to now, this process had not been properly quantified. In principle, the strength of gBGC can be measured from the analysis of derived allele frequency ...read more

    Mentioned in this Paper

    Gene Polymorphism
    Simulation
    Genetic Polymorphism
    Mutation Abnormality
    Population Group
    11
    1
    Paper Details
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