Quantification of Intracranial Aneurysm Volume Pulsation with 7T MRI

AJNR. American Journal of Neuroradiology
R KleinloogB H Verweij

Abstract

Aneurysm volume pulsation is a potential predictor of intracranial aneurysm rupture. We evaluated whether 7T MR imaging can quantify aneurysm volume pulsation. In Stage I of the study, 10 unruptured aneurysms in 9 patients were studied using a high-resolution (0.6-mm, isotropic) 3D gradient-echo sequence with cardiac gating. Semiautomatic segmentation was used to measure aneurysm volume (in cubic millimeters) per cardiac phase. Aneurysm pulsation was defined as the relative increase in volume between the phase with the smallest volume and the phase with the largest volume. The accuracy and precision of the measured volume pulsations were addressed by digital phantom simulations and a repeat image analysis. In Stage II, the imaging protocol was optimized and 9 patients with 9 aneurysms were studied with and without administration of a contrast agent. The mean aneurysm pulsation in Stage I was 8% ± 7% (range, 2%-27%), with a mean volume change of 15 ± 14 mm3 (range, 3-51 mm3). The mean difference in volume change for the repeat image analysis was 2 ± 6 mm3. The artifactual volume pulsations measured with the digital phantom simulations were of the same magnitude as the volume pulsations observed in the patient data, even after pr...Continue Reading

References

Nov 1, 1990·AJR. American Journal of Roentgenology·T C LarsonF W Wehrli
Jul 15, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J M Bland, D G Altman
May 24, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P van OoijA J Nederveen
Aug 14, 2012·Academic Radiology·Azadeh FirouzianWiro J Niessen
Sep 26, 2014·Neurosurgery·Rachel KleinloogBon H Verweij
May 2, 2015·AJNR. American Journal of Neuroradiology·A E VanrossommeK Zouaoui Boudjeltia

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