Quantification of left atrial volume and phasic function using cardiovascular magnetic resonance imaging-comparison of biplane area-length method and Simpson's method

The International Journal of Cardiovascular Imaging
Laura Kristin WandeltWieland Staab

Abstract

Left atrial (LA) enlargement and dysfunction are markers of chronic diastolic dysfunction and an important predictor of adverse cardiovascular and cerebrovascular outcomes. Accordingly, accurate quantification of left atrial volume (LAV) and function is needed. In routine clinical cardiovascular magnetic resonance (CMR) imaging the biplane area-length method (Bi-ALM) is frequently applied due to time-saving image acquisition and analysis. However, given the varying anatomy of the LA we hypothesized that the diagnostic accuracy of the Bi-ALM is not sufficient and that results would be different from a precise volumetric assessment of transversal multi-slice cine images using Simpson's method. Thirty one patients of the FIND-AFRANDOMISED-study with status post acute cerebral ischemia (mean age 70.5 ± 6.2 years) received CMR imaging at 3T. The study protocol included cine SSFP sequences in standard 2- and 4 CV and a stack of contiguous slices in transversal orientation. Total, passive and active LA emptying fractions were calculated from LA maximal volume, minimal volume and volume prior to atrial contraction. Intra- and inter-observer variability was assessed in ten patients. Significant differences were found for LA volume and p...Continue Reading

References

Jan 14, 2005·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Burkhard SieversHans-Joachim Trappe
Dec 16, 2005·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Lucy E HudsmithStefan Neubauer
Jun 21, 2007·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·L E HudsmithS Neubauer
May 22, 2010·Journal of Cardiovascular Electrophysiology·Irene E HofPeter Loh
Nov 13, 2010·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Alicia M MaceiraDudley J Pennell
Dec 13, 2012·Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology·Marcelo Souto NacifCarlos Eduardo Rochitte
Sep 10, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Johannes Tammo KowallickAndreas Schuster
Apr 25, 2015·Stroke; a Journal of Cerebral Circulation·Shadi YaghiMitchell S V Elkind
May 1, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Nadine Kawel-BoehmDavid A Bluemke
May 20, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Johannes T KowallickAndreas Schuster
Feb 12, 2017·Lancet Neurology·Rolf WachterUNKNOWN Find-AF(randomised) Investigators and Coordinators

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Citations

Jan 17, 2019·European Heart Journal Cardiovascular Imaging·Sören J BackhausAndreas Schuster
Mar 4, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Litten BertelsenJesper Hastrup Svendsen
Jul 21, 2020·ESC Heart Failure·Josephine KermerJeanette Schulz-Menger
Apr 14, 2018·The International Journal of Cardiovascular Imaging·Johan H C ReiberNico R L Van de Veire
May 20, 2019·Current Treatment Options in Cardiovascular Medicine·Aaron Soufer, Lauren A Baldassarre
Oct 19, 2020·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Zhi LiuBo Chen
May 5, 2021·The Journal of International Medical Research·Zhi-Song ChenXue-Bo Liu

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