Quantification of lung tumor rotation with automated landmark extraction using orthogonal cine MRI images

Physics in Medicine and Biology
Chiara PaganelliPaul Keall

Abstract

The quantification of tumor motion in sites affected by respiratory motion is of primary importance to improve treatment accuracy. To account for motion, different studies analyzed the translational component only, without focusing on the rotational component, which was quantified in a few studies on the prostate with implanted markers. The aim of our study was to propose a tool able to quantify lung tumor rotation without the use of internal markers, thus providing accurate motion detection close to critical structures such as the heart or liver. Specifically, we propose the use of an automatic feature extraction method in combination with the acquisition of fast orthogonal cine MRI images of nine lung patients. As a preliminary test, we evaluated the performance of the feature extraction method by applying it on regions of interest around (i) the diaphragm and (ii) the tumor and comparing the estimated motion with that obtained by (i) the extraction of the diaphragm profile and (ii) the segmentation of the tumor, respectively. The results confirmed the capability of the proposed method in quantifying tumor motion. Then, a point-based rigid registration was applied to the extracted tumor features between all frames to account ...Continue Reading

References

Dec 1, 1995·International Journal of Radiation Oncology, Biology, Physics·M van HerkJ V Lebesque
Apr 24, 2001·International Journal of Radiation Oncology, Biology, Physics·K M Langen, D T Jones
Jan 31, 2004·Seminars in Radiation Oncology·Hiroki ShiratoShinichi Shimizu
Jul 6, 2004·International Journal of Radiation Oncology, Biology, Physics·Christian PlathowHans-Ulrich Kauczor
Dec 14, 2004·International Journal of Radiation Oncology, Biology, Physics·Nicholas KochCraig W Stevens
Dec 14, 2004·International Journal of Radiation Oncology, Biology, Physics·H Helen LiuCraig W Stevens
Aug 20, 2005·The British Journal of Radiology·C PlathowH-U Kauczor
Oct 3, 2006·The Lancet Oncology·Laura A Dawson, Michael B Sharpe
Nov 23, 2006·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Hans-Ulrich Kauczor, Christian Plathow
Feb 20, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Matthias GuckenbergerMichael Flentje
Oct 20, 2009·International Journal of Radiation Oncology, Biology, Physics·Jin Sheng LiChang-Ming Ma
Oct 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Erik-Jan RijkhorstJan-Jakob Sonke
Jun 2, 2011·Physics in Medicine and Biology·Laura I CerviñoSteve B Jiang
Oct 22, 2011·International Journal of Radiation Oncology, Biology, Physics·Junqing WuPaul J Keall
Jan 31, 2012·International Journal of Radiation Oncology, Biology, Physics·Simon RitJan-Jakob Sonke
Nov 21, 2012·Nature Reviews. Clinical Oncology·David A Jaffray
Nov 21, 2012·Physics in Medicine and Biology·Stine S Korreman
Sep 17, 2013·Journal of Applied Clinical Medical Physics·Mark K H ChanSherry C Y Ng
Feb 4, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Yun YangJing Cai
Jun 17, 2014·Seminars in Radiation Oncology·Biagio Gino Fallone
Jun 17, 2014·Seminars in Radiation Oncology·Paul J KeallUNKNOWN Australian MRI-Linac Program, including contributors from Ingham Institute, Illawarra Cancer Care Centre, Liverpool Hospital
Jun 17, 2014·Seminars in Radiation Oncology·Jan J W LagendijkMarco van Vulpen
Jun 17, 2014·Seminars in Radiation Oncology·Patrick Kupelian, Jan-Jakob Sonke
Nov 6, 2014·Medical Physics·Tianwu Xie, Habib Zaidi
Dec 3, 2014·International Journal of Radiation Oncology, Biology, Physics·Chen-Yu HuangPaul Keall
Mar 11, 2015·International Journal of Radiation Oncology, Biology, Physics·Chiara PaganelliMarco Riboldi

❮ Previous
Next ❯

Citations

Jan 10, 2019·Physics in Medicine and Biology·Noemi GarauChiara Paganelli
Jun 22, 2019·Physics in Medicine and Biology·Jenny BertholetUwe Oelfke
Jul 20, 2019·Physics in Medicine and Biology·C PaganelliG Baroni
Jan 8, 2016·Physics in Medicine and Biology·M SeregniM Riboldi
Dec 29, 2020·Physics in Medicine and Biology·Xingyu NieGuang Li
Jun 3, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Charalampos KalantzopoulosGuido Baroni
Jul 31, 2021·Biomedical Physics & Engineering Express·Fumitake FujiiTakehiro Shiinoki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.