Quantification of myocardial perfusion using CMR with a radial data acquisition: comparison with a dual-bolus method.

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
Tae Ho KimEdward V R DiBella

Abstract

Quantitative estimates of myocardial perfusion generally require accurate measurement of the arterial input function (AIF). The saturation of signal intensity in the blood that occurs with most doses of contrast agent makes obtaining an accurate AIF challenging. This work seeks to evaluate the performance of a method that uses a radial k-space perfusion sequence and multiple saturation recovery times (SRT) to quantify myocardial perfusion with cardiovascular magnetic resonance (CMR). Perfusion CMR was performed at 3 Tesla with a saturation recovery radial turboFLASH sequence with 72 rays. Fourteen subjects were given a low dose (0.004 mmol/kg) of dilute (1/5 concentration) contrast agent (Gd-BOPTA) and then a higher non-dilute dose of the same volume (0.02 mmol/kg). AIFs were calculated from the blood signal in three sub-images with differing effective saturation recovery times. The full and sub-images were reconstructed iteratively with a total variation constraint. The images from the full 72 ray data were processed to obtain six tissue enhancement curves in two slices of the left ventricle in each subject. A 2-compartment model was used to determine absolute flows The proposed multi-SRT method resulted in AIFs that were simi...Continue Reading

References

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Citations

Oct 5, 2011·The International Journal of Cardiovascular Imaging·Edward V R DiBellaSheldon E Litwin
Sep 15, 2011·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Dudley J PennellSanjay K Prasad
Nov 20, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Dudley J PennellSanjay K Prasad
Apr 13, 2013·Radiology·Jonathan A ScheskeJonathon A Leipsic
Dec 8, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Lukas WissmannSebastian Kozerke
Mar 30, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jacob U FluckigerEdward V R DiBella
Feb 2, 2013·Journal of Magnetic Resonance Imaging : JMRI·Jacob U FluckigerDaniel C Lee
Oct 15, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·David ChenDebiao Li
Jun 11, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·David ChenDebiao Li
Sep 18, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·David ChenDebiao Li
Apr 17, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Javier Sánchez-GonzálezBorja Ibañez
Mar 1, 2014·Physiological Measurement·M HussoJ Kuikka
Sep 29, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Johannes Tran-GiaHerbert Köstler

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Methods Mentioned

BETA
saturation
saturation recovery

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