Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques

Investigative Radiology
Nina F SchwenzerFritz Schick

Abstract

The goal of the present study was the assessment of pancreatic and hepatic fat content applying 2 established magnetic resonance (MR) imaging techniques: in-phase/opposed-phase gradient-echo MR imaging and fat-selective spectral-spatial gradient-echo imaging. Results of both approaches were compared, and influences of T1- and T2*-related corrections were assessed. The possibility of a correlation between pancreatic lipomatosis and liver steatosis was investigated. Seventeen volunteers at risk for type 2 diabetes (6 male, 11 female; age, 26-70 years; body mass index, 19.4-41.3 kg/m2; mean, 31.7 kg/m2) were examined. Liver and pancreas fat content were quantified with 2 different gradient-echo techniques: one uses a spectral-spatial excitation technique with 6 binomial radio frequency pulses, which combines chemical shift selectivity with simultaneous slice-selective excitation. The other technique based on double-echo chemical shift gradient-echo MR provides in- and opposed-phase images simultaneously. Influences of T1 and individual T2* effects on results using in-phase/opposed-phase imaging were estimated and corrected for, based on additional T2* measurements. The fat content calculated from images recorded with the fat-selec...Continue Reading

References

Feb 1, 1991·AJR. American Journal of Roentgenology·H LevensonR Buxton
Apr 1, 1991·Radiology·R T ThamC B Lamers
Feb 1, 1991·Investigative Radiology·E L SiegelJ H McMillan
Oct 1, 1984·Radiology·W T Dixon
Dec 1, 1981·Pathology, Research and Practice·P Schmitz-MoormannW Heinze
Jan 1, 1997·Magnetic Resonance Imaging·M H FishbeinM A Smith
Aug 1, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·F SchickC D Claussen
Apr 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·M ShimabukuroR H Unger
Mar 4, 2000·Journal of Pediatric Gastroenterology and Nutrition·J FeigelsonC Ferec
Feb 7, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·R H Unger, L Orci
Apr 12, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Fritz SchickStephan Jacob
Dec 28, 2002·Diabetes·Alexandra E ButlerPeter C Butler
Jul 4, 2003·Current Opinion in Lipidology·Jean E Schaffer
Apr 6, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xiaowei ZhangG Allan Johnson
Jul 21, 2004·Hypertension·Anna Maria SironiEle Ferrannini
Dec 14, 2004·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·L HeilbronnE Ravussin
Jan 20, 2005·Gastroentérologie Clinique Et Biologique·Dominique A VuittonGeorges A Mantion
Mar 24, 2005·Pediatric Radiology·Arzu KovanlikayaVicente Gilsanz
May 4, 2005·Academic Radiology·Arzu KovanlikayaVicente Gilsanz
Jul 8, 2005·Journal of Clinical Gastroenterology·Mark FishbeinW Ross Stevens
Mar 1, 2006·Gastroentérologie Clinique Et Biologique·Frank PilleulPierre-Jean Valette
Mar 1, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jürgen MachannFritz Schick
Jun 8, 2006·Annual Review of Biochemistry·Deborah M Muoio, Christopher B Newgard
Nov 14, 2006·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Joan Campbell-ToftePer Mølgaard
Jan 24, 2007·AJR. American Journal of Roentgenology·Hye Jin KimMoon-Gyu Lee
May 18, 2007·Investigative Radiology·Gerwin P SchmidtStefan O Schoenberg
Jul 27, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chia-Ying LiuScott B Reeder
Aug 2, 2007·Diabetes Care·Maarten E TushuizenMichaela Diamant

❮ Previous
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Citations

Aug 22, 2013·Progress in Nuclear Magnetic Resonance Spectroscopy·E L ThomasJ D Bell
May 26, 2012·Nutrition Research Reviews·E Louise ThomasJimmy D Bell
Feb 10, 2011·Nature Reviews. Gastroenterology & Hepatology·Mark M Smits, Erwin J M van Geenen
May 15, 2013·PloS One·Horng-Yih OuChih-Jen Chang
Apr 1, 2010·World Journal of Gastroenterology : WJG·Fabian SpringerNina F Schwenzer
Apr 27, 2010·World Journal of Gastroenterology : WJG·Paul E SijensRonald P Stolk
Jul 30, 2011·World Journal of Gastroenterology : WJG·Lucia PacificoClaudio Chiesa
Mar 14, 2014·Clinical and Translational Gastroenterology·Mika HoriHitoshi Nakagama
May 16, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sajal S PokharelAtif Zaheer
Oct 13, 2015·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Abigail E VallanceAndrew M Smith
Jul 11, 2009·Clinical Radiology·A K Banerjee
May 13, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna M G CaliSonia Caprio
Oct 15, 2013·NMR in Biomedicine·H H Hu, H E Kan
Dec 19, 2013·Gastroenterology Research and Practice·Niraj S PatelRohit Loomba
Jan 11, 2017·Postgraduate Medical Journal·Tamara AlempijevicTomica Milosavljevic
Dec 17, 2010·World Journal of Radiology·Santhi Maniam, Janio Szklaruk
Oct 7, 2017·Diabetes/metabolism Research and Reviews·Valeria Guglielmi, Paolo Sbraccia
Feb 28, 2014·Journal of the American Heart Association·Chih-Yuan WangChih-Jen Chang
Sep 28, 2010·Pancreas·Erwin-Jan M van GeenenChris J J Mulder
Feb 18, 2014·The Journal of Clinical Endocrinology and Metabolism·Henri HonkaPirjo Nuutila
Aug 21, 2019·Abdominal Radiology·Anushri Parakh, Temel Tirkes

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