Quantification of regurgitant lesions by MRI

International Journal of Cardiac Imaging
S GlobitsD Glogar

Abstract

We examined 46 patients with angiographically documented regurgitant lesions (26 patients with mitral regurgitation, 20 patients with aortic regurgitation) using an 0.5 Tesla magnet. In each patient a multislice-multiphase spinecho sequence in sagittal-coronal double angulated plane was performed to assess left and right ventricular volumes, ejection fraction and regurgitant fraction. Additionally a blood flow sensitive gradient echo technique was done to visualize direction and extension of the regurgitant jet. MRI data were compared with quantitative and qualitative assessment of regurgitation by angiography and echocardiography. Using the gradient echo technique MRI could demonstrate the regurgitant jet in all patients. A linear correlation for volume parameters by MRI and angio was found with best correlation for the left ventricular stroke volume (r = 0.82, p less than 0.0001). Furthermore MRI regurgitant fraction correlated with angiographically determined regurgitant fraction in patients with aortic regurgitation (r = 0.91, p less than 0.0001) and mitral regurgitation (r = 0.67, p less than 0.001), respectively. Semiquantitative assessment of regurgitation by gradient echo technique showed an agreement with angiographic ...Continue Reading

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Citations

Sep 1, 2007·European Radiology·Pier Giorgio MasciJan Bogaert
Oct 20, 2010·Heart, Lung & Circulation·Jonathan P ChristiansenSaul G Myerson
May 17, 2012·Journal of Magnetic Resonance Imaging : JMRI·Gregor SommerGunnar Lund
May 30, 1998·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·G Z Yang
Oct 8, 2009·Circulation. Cardiovascular Imaging·Stefan BuchnerBehrus Djavidani

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