Quantification of renal allograft perfusion using arterial spin labeling MRI: initial results.

European Radiology
Rotem S LanzmanDirk Blondin

Abstract

To quantify renal allograft perfusion in recipients with stable allograft function and acute decrease in allograft function using nonenhanced flow-sensitive alternating inversion recovery (FAIR)-TrueFISP arterial spin labeling (ASL) MR imaging. Following approval of the local ethics committee, 20 renal allograft recipients were included in this study. ASL perfusion measurement and an anatomical T2-weighted single-shot fast spin-echo (HASTE) sequence were performed on a 1.5-T scanner (Magnetom Avanto, Siemens, Erlangen, Germany). T2-weighted MR urography was performed in patients with suspected ureteral obstruction. Patients were assigned to three groups: group a, 6 patients with stable allograft function over the previous 4 months; group b, 7 patients with good allograft function who underwent transplantation during the previous 3 weeks; group c, 7 allograft recipients with an acute deterioration of renal function. Mean cortical perfusion values were 304.8 +/- 34.4, 296.5 +/- 44.1, and 181.9 +/- 53.4 mg/100 ml/min for groups a, b and c, respectively. Reduction in cortical perfusion in group c was statistically significant. Our results indicate that ASL is a promising technique for nonenhanced quantification of cortical perfusio...Continue Reading

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Citations

Nov 22, 2012·Radiology·Rotem S LanzmanHans-Jörg Wittsack
Sep 19, 2012·Japanese Journal of Radiology·Yoshiaki KatadaMasaya Tamano
Dec 3, 2015·Der Radiologe·R S LanzmanH J Wittsack
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May 19, 2011·Journal of Magnetic Resonance Imaging : JMRI·Nathan S ArtzSean B Fain
Oct 15, 2013·Journal of Magnetic Resonance Imaging : JMRI·Philipp HeuschRotem S Lanzman
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