Quantification of soluble serum HLA class I antigens in healthy volunteers and AIDS patients

Clinica Chimica Acta; International Journal of Clinical Chemistry
A FerreiraP González-Porqué

Abstract

A solid-phase enzyme immunoassay (ELISA) has been used to quantify human soluble Class I histocompatibility antigens in serum samples from voluntary blood donors and AIDS patients. Statistical analysis of the results showed significantly raised levels (p less than 0.01) of free HLA Class I in sera from AIDS patients (2.95 +/- 1.80 micrograms/ml) when compared with the blood donors (1.06 +/- 0.6 micrograms/ml). The assay is specific, reproducible and easy to perform. Potential uses of this determination are discussed.

References

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Citations

Jan 1, 1991·Journal of Clinical Laboratory Analysis·S ComuzioF Indiveri
Dec 1, 1990·Journal of the Neurological Sciences·J C Alvarez-CermeñoP Gonzalez-Porque
Jan 1, 1992·Journal of Neuroimmunology·J C Alvarez-CermeñoP González-Porqué
Feb 25, 1998·Human Immunology·M NocitoL M Villar
Jul 31, 1998·Human Immunology·J C McDonald, I Adamashvili
May 13, 1999·Human Immunology·D AultmanJ McDonald
Jul 17, 1999·Human Immunology·A MinguelaM R Alvarez-López
Oct 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·J Alvarez-CermeñoP González-Porque
Sep 1, 1994·International Journal of STD & AIDS·G Keir
Jul 1, 1990·Acta Neurologica Scandinavica·J C Alvarez-CermeñoP Gonzalez-Porque

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