PMID: 9447913Feb 3, 1998Paper

Quantification of the stria vascularis and strial capillary areas in quiet-reared young and aged gerbils

Hearing Research
M A GrattonN M Smythe

Abstract

The area of the stria vascularis (StV) and of StV capillaries was measured in radial sections from regions corresponding to 0.5, 2, 4, 10, 20 and 40 kHz. In young gerbils, StV area ranged from 3700 to 8500 microm2 and that of individual StV capillaries from 70 to 110 microm2. The maximal StV area as well as the largest number of capillaries occurred at the 20 kHz region. In quiet-aged gerbils, the StV area also varied with frequency and was 28-67% smaller than corresponding measures in young gerbils. The decrease in StV area was statistically significant at all but the 2 and 4 kHz regions. The area of individual StV capillaries declined also (8-29%) with age even when the StV area remained near normal. Reductions in capillary area were statistically significant at the 2, 20 and 40 kHz regions. The large variance in StV radial area among aged gerbils reflects the patchy nature of strial degeneration previously observed in this species. The data agree with those of our previous studies and indicate alterations in StV capillaries are a primary cause of presbyacusis in the gerbil.

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Citations

Aug 29, 2003·Journal of the Association for Research in Otolaryngology : JARO·H LangR A Schmiedt
Dec 13, 2006·Journal of the Association for Research in Otolaryngology : JARO·Gail IshiyamaAkira Ishiyama
Mar 21, 2013·Journal of the Association for Research in Otolaryngology : JARO·Mark A EckertJudy R Dubno
Jul 27, 2001·Hearing Research·A W ScholtzA Schrott-Fischer
Jul 27, 2001·Hearing Research·E M KeithleyN Fischel-Ghodsian
May 29, 2002·Hearing Research·Flint A BoettcherJohn H Mills
Oct 4, 2002·Hearing Research·Samuel S Spicer, Bradley A Schulte
Nov 16, 2002·Hearing Research·Denise LaMarche HeaneyAndrew S Niedzielski
Nov 6, 2003·Hearing Research·Steven SluyterGuido F Smoorenburg
Nov 5, 1997·Hearing Research·G N ThomopoulosB A Schulte
Jun 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Wenjing ZhangXiaorui Shi
Sep 2, 2014·Experimental Gerontology·Moritz GröschelDietmar Basta
Jan 4, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mitsuya SuzukiTatsuya Yamasoba
Mar 17, 2009·Brain Research·Kevin K Ohlemiller
Jul 18, 2006·Hearing Research·Tima Le, Elizabeth M Keithley
Mar 6, 2015·Cell and Tissue Research·Lingling NengXiaorui Shi
Aug 13, 2013·Oxidative Medicine and Cellular Longevity·Makoto KinoshitaTatsuya Yamasoba
Aug 30, 2016·Experimental Gerontology·Otto GleichJürgen Strutz
Oct 18, 2016·Journal of Cellular Physiology·Rahul MittalXue Zhong Liu
Aug 12, 2006·Hearing Research·Kevin K OhlemillerPatricia M Gagnon
Mar 22, 2014·Korean Journal of Audiology·Kyu-Yup Lee
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Sep 21, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·Kevin K Ohlemiller
Mar 15, 2005·Journal of Neuroscience Research·Golda Anne KevetterRobert B Leonard
Jul 25, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Rodney C Diaz
Sep 25, 2004·The Journal of Comparative Neurology·Kevin K Ohlemiller, Patricia M Gagnon
Oct 1, 2021·Journal of the Association for Research in Otolaryngology : JARO·Courtney Coburn GlavinSumitrajit Dhar
Oct 14, 2021·Journal of the Association for Research in Otolaryngology : JARO·Kenyaria NobleHainan Lang

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