PMID: 8948298Nov 1, 1996Paper

Quantified neurological examination with emphasis on motor and sensory functions in patients with rheumatoid arthritis and controls

British Journal of Rheumatology
S I BekkelundG Husby

Abstract

A controlled study of quantified clinical neurological examination, including psychophysical assessment of sensory thresholds, in patients with rheumatoid arthritis (RA) was carried out. Fifty-five women with seropositive RA living in North Norway and 83 healthy controls underwent clinical neurological examination quantified by neurological symptom score (NSS) and neurological deficit score (NDS). Vibration threshold (VT), warm-cold detection threshold (limen) as well as heat pain detection threshold (HPDT) were performed to evaluate afferent myelinated and unmyelinated fibre functions. Higher scores on NSS and NDS were seen in RA patients compared with the controls. Higher index finger and big toe VT was demonstrated in the patients, while results from warm-cold limen and HPDT were not significantly different in the two groups. Among the disease-related variables, the most prominent finding was a positive association of index finger VT with disease duration in the patients (P = 0.01). Maximum walking time (15 m) was a significant predictor of big toe VT in the patient group (P = 0.0001). This study suggests impaired peripheral nerve function in afferent myelinated fibres. However, involvement of dorsal column fibres cannot be ...Continue Reading

Citations

Oct 31, 2012·Current Pain and Headache Reports·David A Walsh, Daniel F McWilliams
Jul 13, 2002·Annals of the New York Academy of Sciences·Luca BertinottiMarco Matucci-Cerinic
Jun 22, 2006·Journal of the Peripheral Nervous System : JPNS·Giovanni AlbaniAlessandro Mauro
May 5, 2012·Arthritis Care & Research·Daniel F McWilliamsDavid A Walsh
Nov 21, 2000·Rheumatic Diseases Clinics of North America·C G BaerwaldA Krause
Aug 13, 2015·Best Practice & Research. Clinical Rheumatology·Fabiola AtzeniPiercarlo Sarzi-Puttini
Jan 26, 2006·QJM : Monthly Journal of the Association of Physicians·N SofatC S Higgens
Jul 29, 2000·Seminars in Pediatric Neurology·N F Schor

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