Quantifying annual internal effective 137 Cesium dose utilizing direct body-burden measurement and ecological dose modeling

Journal of Exposure Science & Environmental Epidemiology
Benjamin A JelinErik R Svendsen

Abstract

The Chernobyl Nuclear Power Plant (CNPP) accident represents one of the most significant civilian releases of 137Cesium (137Cs, radiocesium) in human history. In the Chernobyl-affected region, radiocesium is considered to be the greatest on-going environmental hazard to human health by radiobiologists and public health scientists. The goal of this study was to characterize dosimetric patterns and predictive factors for whole-body count (WBC)-derived radiocesium internal dose estimations in a CNPP-affected children's cohort, and cross-validate these estimations with a soil-based ecological dose estimation model. WBC data were used to estimate the internal effective dose using the International Commission on Radiological Protection (ICRP) 67 dose conversion coefficient for 137Cs and MONDAL Version 3.01 software. Geometric mean dose estimates from each model were compared utilizing paired t-tests and intra-class correlation coefficients. Additionally, we developed predictive models for WBC-derived dose estimation in order to determine the appropriateness of EMARC to estimate dose for this population. The two WBC-derived dose predictive models identified 137Cs soil concentration (P<0.0001) as the strongest predictor of annual inter...Continue Reading

References

Feb 11, 2005·Radiation Protection Dosimetry·Naoko MoritaYutaka Okumura
Jul 13, 2006·Journal of Environmental Radioactivity·M V KadukaP Strand
Sep 30, 2006·Journal of Environmental Radioactivity·G PröhlG Zibold
Nov 30, 2007·Archives of Toxicology·Elise GrignardMaâmar Souidi
Feb 15, 2008·Radiation and Environmental Biophysics·A P Kravets, Yu A Pavlenko
Jun 4, 2008·Environmental Health : a Global Access Science Source·Julie FontaineSerge Déry
Jan 27, 2010·Environmental Health Perspectives·Erik R SvendsenWilfried J J Karmaus
Sep 29, 2011·Journal of Radiation Research·Naomi HayashidaNoboru Takamura
Feb 4, 2012·Journal of Radiation Research·Stéphane GrisonMaâmar Souidi

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