Quantifying blood flow and wall shear stresses in the outflow tract of chick embryonic hearts

Computers & Structures
Aiping LiuSandra Rugonyi

Abstract

Wall shear stresses (WSS) exerted by blood flow on cardiac tissues modulate growth and development of the heart. To study the role of hemodynamic conditions on cardiac morphogenesis, here, we present a methodology that combines imaging and finite element modeling to quantify the in vivo blood flow dynamics and WSS in the cardiac outflow tract (OFT) of early chicken embryos (day 3 out of 21-day incubation period). We found a distinct blood flow field and heterogeneous distribution of WSS in the chicken embryonic heart OFT, which have physiological implications for OFT morphogenesis.

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Citations

Jul 5, 2012·Biomechanics and Modeling in Mechanobiology·Sevan GoenezenSandra Rugonyi
Apr 27, 2012·Annals of Biomedical Engineering·Koonal N BharadwajJonathan T Butcher
Apr 19, 2016·Journal of Cardiovascular Development and Disease·Venkat Keshav ChivukulaSandra Rugonyi
Feb 16, 2016·Journal of Cardiovascular Development and Disease·Vinal MenonJay D Potts
Jul 7, 2012·Ultrasound in Medicine & Biology·Telli FaezNico de Jong
May 29, 2014·Developmental Dynamics : an Official Publication of the American Association of Anatomists·William J KowalskiKerem Pekkan
Oct 16, 2015·Journal of the Royal Society, Interface·Madeline MidgettSandra Rugonyi
Sep 13, 2015·Biomechanics and Modeling in Mechanobiology·Sevan GoenezenSandra Rugonyi
Jul 6, 2014·Frontiers in Physiology·Stefanie V BiechlerRichard L Goodwin
Nov 7, 2014·Frontiers in Physiology·William J KowalskiBradley B Keller
Aug 29, 2014·Journal of the Royal Society, Interface·Madeline MidgettSandra Rugonyi
Feb 15, 2018·Journal of Cardiovascular Development and Disease·Taylor B LawsonMonica T Hinds
Sep 9, 2016·Physiological Reviews·Graham J BurtonKent L Thornburg
May 27, 2016·Journal of Biomedical Optics·Raksha RaghunathanKirill V Larin
Nov 16, 2013·Journal of Biomechanical Engineering·Brennan M JohnsonLakshmi Prasad Dasi
Feb 28, 2019·Biomechanics and Modeling in Mechanobiology·Sheldon HoChoon Hwai Yap
Apr 29, 2020·Biomedical Optics Express·Shang WangKirill V Larin
Mar 2, 2019·Journal of Cardiovascular Development and Disease·Katherine CourchaineSandra Rugonyi
Sep 9, 2017·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Vinal MenonJay D Potts
Oct 6, 2020·Biomedical Optics Express·Sahar ElahiMichael W Jenkins
Nov 20, 2012·Biomedical Optics Express·Lindsy M PetersonAndrew M Rollins
Feb 13, 2021·Journal of Cardiovascular Development and Disease·Huseyin Enes Salman, Huseyin Cagatay Yalcin

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