Quantifying electrosurgery-induced thermal effects and damage to human tissue: an exploratory study with the fallopian tube as a novel in-vivo in-situ model

Journal of Minimally Invasive Gynecology
Christian WallwienerMarkus Wallwiener

Abstract

To develop a human in vivo in situ model for analyzing the extent and the basic mechanisms of thermal spread and thermal tissue damage. Prospective, open, uncontrolled, nonrandomized, single-center exploratory study. University hospital. Eighteen adult patients undergoing open abdominal hysterectomy for benign disease. Unilateral fallopian tube tissue desiccation (10 seconds) with a laparoscopic bipolar clamp at routine settings. Deep tissue temperature (thermal probe), tissue surface temperature (thermal camera), and gross and histologic assessments of lesions with a newly developed composite scoring system. Fifteen specimens from 18 patients were evaluated. Lateral thermal damage (LTD; determined by lactate dehydrogenase staining), was strongly correlated with maximum desiccation temperature. Deep tissue LTD and surface LTD were linearly related. Histologic and macroscopic criteria for thermal effects and damage and the corresponding scores proved functional and strongly correlated with LTD. Measurement of deep tissue and tissue surface temperatures consistently yielded complete temporal and spatial temperature distributions that were describable by the heat equation. Our novel in vivo in situ model allows standardized, repro...Continue Reading

References

Feb 1, 2003·Annals of Surgery·Tarek A Emam, Alfred Cuschieri
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Jul 23, 2003·Surgical Endoscopy·P A CampbellA Cuschieri
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Dec 20, 2005·Fertility and Sterility·Avner Hershlag, Jacob Markovitz
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Apr 28, 2007·Fertility and Sterility·Christian WallwienerWolfgang Zubke
Oct 8, 2008·Journal of Clinical Pathology·B Clarke, W G McCluggage

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