Quantifying losses to the donated blood supply due to donor deferral and miscollection

Transfusion
Brian CusterMichael P Busch

Abstract

Donors are deferred for multiple reasons. Losses related to disease marker rates are well established. Donor and donation losses for other reasons, however, have not been extensively quantified. To quantify these losses, three data sets from the Blood Centers of the Pacific were combined, permitting detailed analysis of year 2000 allogeneic whole-blood donations. During 2000, 13.6 percent of 116,165 persons who presented for donation were deferred at presentation. Short-term deferral accounted for 68.5 percent (hematocrit was most common at 60%); long-term deferral accounted for 21 percent (travel to a malarial area and tattoo or other nonintravenous drug use needle exposure were most common at 59 and 29%, respectively); and multiple-year or permanent deferral accounted for 10.5 percent (UK travel [variant Creutzfeldt-Jakob disease] risk and emigration from a malarial area were most common at 38 and 11%, respectively). Disease-marker-reactive donations represented 0.9 percent of donor outcomes. The prevalence of deferral and also miscollection (under- and overweight units) varied by age, sex, and first-time versus repeat donor status. Overall, miscollection led to a loss of 3.8 percent of 100,141 collections, ranging from 1.9 p...Continue Reading

References

Jan 1, 1988·Vox Sanguinis·J V LindenR I Kalish
Mar 1, 1987·Transfusion·J A Piliavin
May 1, 1985·Transfusion·J B AuBuchon
Dec 15, 1995·American Journal of Epidemiology·S Greenland, W D Finkle
Mar 1, 1996·Transfusion Medicine·R C James, D E Matthews
Mar 26, 1997·JAMA : the Journal of the American Medical Association·A E WilliamsG J Nemo
Jul 8, 1999·European Journal of Epidemiology·S Lawson-Ayayi, L R Salmi
Nov 22, 2000·Annals of Medicine·R Y Dodd
Dec 1, 2000·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·K ColganK Witte
Mar 29, 2001·Transfusion·Y WuUNKNOWN Retrovirus Epidemiology Donor Study (REDS) Group
Jun 16, 2001·Transfusion·G B SchreiberUNKNOWN Retrovirus Epidemiology Donor Study
Jul 27, 2001·Transfusion Medicine Reviews·B Newman
Sep 19, 2002·American Journal of Therapeutics·Marc Germain, Mindy Goldman

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Citations

Sep 23, 2010·Asian Journal of Transfusion Science·Naveen Agnihotri
Sep 23, 2010·Asian Journal of Transfusion Science·P SundarN Shivanna
Dec 22, 2009·Biologicals : Journal of the International Association of Biological Standardization·Marinus van HulstMaarten J Postma
Aug 25, 2015·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Bushra MoizMadeeha Anwar
Mar 27, 2007·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·R B SawantS B Rajadhyaksha
Jun 11, 2009·Vox Sanguinis·I J T VeldhuizenW L A M De Kort
Jul 28, 2007·Transfusion·Brian CusterEdward L Murphy
Jan 28, 2009·Transfusion·Mindy GoldmanSheila F O'Brien
Jan 30, 2009·Transfusion·Cláudia Di Lorenzo OliveiraAnna B F Carneiro-Proietti
Dec 11, 2007·Transfusion Medicine·O MarantidouA Maniatis
Dec 11, 2007·Vox Sanguinis·A H MisjeH E Heier
Dec 12, 2007·Vox Sanguinis·J RingwaldR Eckstein
Oct 28, 2010·Transfusion·Meghan DelaneyAlan E Mast
Sep 29, 2011·Transfusion·Brian CusterUNKNOWN NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II)
May 29, 2013·British Journal of Haematology·Axel Seltsam, Thomas H Müller
Jul 12, 2012·Transfusion·Maxime Diane KouaoJean-Jacques Lefrère
Sep 8, 2011·Transfusion·Nan GuoUNKNOWN NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component
Mar 11, 2011·Transfusion·Gary M Brittenham
Mar 26, 2013·Transfusion Medicine·A-M Batiha, M AlBashtawy
Jul 31, 2013·Transfusion·Wim de KortTanneke Marijt-van der Kreek
May 3, 2015·Transfusion Medicine Reviews·Sheila F O'BrienDavid A Leiby
Aug 29, 2014·São Paulo Medical Journal = Revista Paulista De Medicina·Leila Kasraian, Neda Negarestani
Sep 15, 2005·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Brian CusterMichael P Busch
Jul 25, 2019·BMC Health Services Research·Henshaw Uchechi Okoroiwu, Enosakhare Aiyudubie Asemota
Mar 6, 2021·Health Care Management Science·W Alton RussellMargaret L Brandeau
Mar 19, 2021·American Journal of Public Health·William RileyJeffrey McCullough
Apr 28, 2006·Journal of Psychosocial Nursing and Mental Health Services·Teena M McGuinness

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