PMID: 8599295Jan 1, 1995

Quantifying pulmonary oxygen transfer deficits in critically ill patients

Acta Anaesthesiologica Scandinavica. Supplementum
J H Wandrup

Abstract

The clinical picture describing oxygen transfer deficits in literature is complicated by inconsistent terminology, and a weak perception of the influence total errors of measured and estimated values have on clinical decision-making. Clinical and analytical terminology: Terms like hypoxia, hypoxaemia and tissue hypoxia in clinical literature are often used synonymously. In present terminology, arterial hypoxia (pO2(a)) is considered to be based on measurements of oxygen tension in arterial blood. On the other hand, arterial hypoxaemia (ctO2(a)) is considered to be based on measurements of both pO2, total haemoglobin (ctHb), saturation (sO2), carboxyhaemoglobin (FCOHb), and methaemoglobin (FMetHb). Arterial hypoxia is simply a low oxygen tension in arterial blood. Arterial hypoxaemia is thus simply a low oxygen concentration in arterial blood. Pulmonary indices: The tension-based indices. At the bedside, assessment of the oxygen uptake in the lungs has been evaluated by calculating indices like pO2(a)/FO2(I),pO2(A-a),pO2(a/A) and the respiratory index (RI = pO2(A-a)/pO2(a)). The different oxygen tension-based indices all require the calculation of the alveolar oxygen tension from the alveolar equation. These calculations involve...Continue Reading

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Jan 1, 1995·Acta Anaesthesiologica Scandinavica. Supplementum·O Siggaard-Andersen, I H Gøthgen
Nov 27, 2010·Biomedical Engineering Online·Ashwath SundaresanGeoffrey M Shaw
Nov 6, 2010·Medical Engineering & Physics·Dan S KarbingS E Rees
Apr 17, 2003·Intensive Care Medicine·Søren KjaergaardS Andreassen
Feb 19, 2016·Clinical Hemorheology and Microcirculation·Marijke GrauFrank Suhr
Jan 10, 2018·Expert Review of Vaccines·Július RajčániSusan Szathmary
May 18, 2016·Anesthesia and Analgesia·Gerardo TusmanFernando Suarez-Sipmann

Related Concepts

Anoxemia
Carboxyhemoglobin C
Pulmonary Artery Catheterization
Eryhem
Lung
Methemoglobin
Dioxygen
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Pulmonary Alveolar Structure
Pulmonary Gas Exchange

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