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Quantifying selection in immune receptor repertoires

bioRxiv

Apr 21, 2014

Yuval ElhanatiAleksandra M Walczak

Abstract

The efficient recognition of pathogens by the adaptive immune system relies on the diversity of receptors displayed at the surface of immune cells. T-cell receptor diversity results from an initial random DNA editing process, called VDJ recombination, followed by functional selection of...read more

Mentioned in this Paper

Immune System
Surface
Antibody Repertoire
V(D)J Recombination
Memory
Peptides
Immune Effector Cell
Beta protein
Randomization
T-Cell Receptor
3
5
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Quantifying selection in immune receptor repertoires

bioRxiv

Apr 21, 2014

Yuval ElhanatiAleksandra M Walczak

PMID: 990004341

DOI: 10.1101/004341

Abstract

The efficient recognition of pathogens by the adaptive immune system relies on the diversity of receptors displayed at the surface of immune cells. T-cell receptor diversity results from an initial random DNA editing process, called VDJ recombination, followed by functional selection of...read more

Mentioned in this Paper

Immune System
Surface
Antibody Repertoire
V(D)J Recombination
Memory
Peptides
Immune Effector Cell
Beta protein
Randomization
T-Cell Receptor
3
5

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