Abstract
Individuals differ in forearm length. As microstructure differs along the radius, we hypothesized that errors may occur when sexual and racial dimorphisms are quantified at a fixed distance from the radio-carpal joint. Microstructure was quantified ex vivo in 18 cadaveric radii using high resolution peripheral quantitative computed tomography and in vivo in 158 Asian and Caucasian women and men at a fixed region of interest (ROI), a corrected ROI positioned at 4.5-6% of forearm length and using the fixed ROI adjusted for cross sectional area (CSA), forearm length or height. Secular effects of age were assessed by comparing 38 younger and 33 older women. Ex vivo, similar amounts of bone mass fashioned adjacent cross sections. Larger distal cross sections had thinner porous cortices of lower matrix mineral density (MMD), a larger medullary CSA and higher trabecular density. Smaller proximal cross-sections had thicker less porous cortices of higher MMD, a small medullary canal with little trabecular bone. Taller persons had more distally positioned fixed ROIs which moved proximally when corrected. Shorter persons had more proximally positioned fixed ROIs which moved distally when corrected, so dimorphisms lessened. In the correcte...Continue Reading
Citations
Jul 13, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Ka Yee CheukEgo Seeman
Oct 24, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W WangW Xia
Apr 14, 2020·PloS One·Maria UnwinLeigh Kinsman
May 28, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D E WhittierM L Bouxsein
May 3, 2019·JBMR Plus·Roger ZebazeEgo Seeman
May 3, 2019·JBMR Plus·Melissa SumMarcella Walker
Sep 7, 2018·Current Osteoporosis Reports·Sabashini K Ramchand, Ego Seeman
Dec 11, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Roland ChapurlatEgo Seeman
Jul 3, 2018·Bone Reports·Megan E MancusoKaren L Troy
Apr 1, 2021·Bone Reports·Karen L TroyThomas J Schnitzer
Feb 10, 2021·Bone·Nicholas MikolajewiczBettina M Willie
Apr 26, 2021·Bone·Narihiro OkazakiMakoto Osaki
Mar 12, 2021·The Journal of Clinical Endocrinology and Metabolism·Mark Ng Tang FuiMathis Grossmann
Oct 1, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S J WardenS M Moe