Quantifying the effects of age, gender, degeneration, and adjacent level degeneration on cervical spine range of motion using multivariate analyses

Spine
Andrew K SimpsonJonathan N Grauer

Abstract

Retrospective review and multivariate analysis. Assess cervical spine segmental range of motion (ROM) with flexion/extension (F/E) radiographs and determine the relation to clinical variables. Previous studies investigated the roles of age and degeneration on cervical ROM with univariate analyses. Multivariate analyses are required to account for multiple factors that may affect ROM and quantify their relative effects. Radiographs of 195 patients were analyzed, including 133 females and 62 males with ages ranging from 15 to 93 years. Segmental ROM and Kellgren score (KS) of degeneration were assessed for C2-C7. Patient's age and gender were documented. Multivariate analyses were performed for each level. Independent variables evaluated were: (1) KS at the level of interest, (2) KS at the level above, (3) KS at the level below, (4) age, and (5) gender. Significance was defined as P < 0.05. Interobserver reliabilities for assessing KS (intraclass correlation coefficient 0.81) and segmental ROM (intraclass correlation coefficient 0.72) were good to excellent. Age had a significant negative association with ROM at C2-C3, C3-C4, C4-C5, and C5-C6. KS at the level of interest had a significant negative association with ROM at C2-C3, C...Continue Reading

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Citations

Jan 25, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Xiao-Dong WuYuan-Yuan Chen
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