Quantifying viscoelasticity of gelatin phantoms by measuring impulse response using compact optical sensors

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Bo QiangXiaoming Zhang

Abstract

Tissue elastography measures tissue mechanical properties, which contain important physiological information and help medical diagnosis. Instead of tracking shear wave propagation inside tissue as do magnetic resonance elastography and ultrasound based techniques, this study focuses on monitoring the propagation of surface Raleigh waves stimulated by short impulses. The method is noncontact, noninvasive, and low cost and has a potential for clinical applications. A customized device designed to measure surface wave propagation is constructed based on a laser displacement sensor (LDS). Experiments are carried out on two porcine skin gelatin phantoms of different concentrations. For each phantom, the phase velocities of specific frequencies are extracted using a cross-spectrum method and then the material elasticity and viscosity are found by fitting the phase velocities with the Voigt's model. The results suggest that measuring viscoelasticity by monitoring the response to a surface impulse is an efficient method because of the richness of frequency content of impulse responses. The results are validated with a standard continuous wave (CW) method.

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Citations

Jan 10, 2012·The Journal of the Acoustical Society of America·Thomas J RoystonRichard L Magin
Mar 29, 2014·Medical Engineering & Physics·Yubo GuanMingxi Wan
Oct 5, 2010·Medical Engineering & Physics·Xiaoming ZhangJames F Greenleaf
Jul 20, 2011·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Bo QiangXiaoming Zhang
Nov 22, 2012·Computer Methods in Biomechanics and Biomedical Engineering·Xiaodong Zhao, Assimina A Pelegri
Oct 20, 2017·Critical Care : the Official Journal of the Critical Care Forum·Kianoush B KashaniXiaoming Zhang

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