PMID: 6401995Feb 1, 1983Paper

Quantitation and detection of isotypes of anti-SS-B antibodies by ELISA and Farr assays using affinity purified antigens. An approach to the investigation of Sjögren's syndrome and systemic lupus erythematosus

Arthritis and Rheumatism
P J VenablesR N Maini

Abstract

Affinity purified SS-B was characterized as a protein with immunoreactive polypeptides of 40K and 29K. A modified Farr assay and an enzyme linked immunosorbent assay (ELISA) were 100- to 1,000-fold more sensitive than immunodiffusion and showed an association with the systemic manifestations of primary sicca syndrome and Sjögren's syndrome with systemic lupus erythematosus. The ELISA was sufficiently sensitive to detect class specific antibodies in saliva and lymphocyte culture supernatants.

References

Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M R Lerner, J A Steitz
Aug 1, 1981·Cell·M R Lerner, J A Steitz
May 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·E A LernerJ A Steitz
Jan 1, 1982·Scandinavian Journal of Immunology·A M TeppoO Wegelius

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Citations

Jan 1, 1984·Rheumatology International·P R SmithR N Maini
Sep 1, 1986·Journal of Clinical Immunology·M Reichlin
Jun 1, 1987·Clinical Rheumatology·D Williams
Sep 4, 1984·Journal of Immunological Methods·H Towbin, J Gordon
Sep 27, 1986·Journal of Immunological Methods·M Gripenberg, P Kurki
Nov 23, 1987·Journal of Immunological Methods·A C HorsfallR N Maini
Apr 25, 1991·Journal of Immunological Methods·R SlobbeW J Van Venrooij
Dec 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·J A Hardin, J O Thomas
Jan 1, 1988·Annals of the Rheumatic Diseases·P J VenablesR N Maini
Mar 1, 1987·The Journal of Clinical Investigation·K K GaitherJ B Harley
Jan 1, 1985·Scandinavian Journal of Rheumatology. Supplement·S O Hoch
Jan 1, 1985·Scandinavian Journal of Rheumatology. Supplement·R N MainiP J Venables
Aug 1, 1989·Journal of Autoimmunity·A C HorsfallR N Maini
Jul 20, 2007·Brazilian Dental Journal·Carmelinda Schmidt UnterkircherYasmin Rodarte Carvalho
Jul 1, 1985·Clinics in Dermatology·K B Kulick, M Reichlin
May 1, 1986·Arthritis and Rheumatism·R I FoxF V Howell
Feb 1, 1986·Arthritis and Rheumatism·J B HarleyF C Arnett
Feb 1, 1984·Arthritis and Rheumatism·R W HoffmanS E Walker

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