PMID: 3745717Sep 1, 1986Paper

Quantitation of regional myocardial function by cine computed tomography: pharmacologic changes in wall thickness

Journal of the American College of Cardiology
P LanzerC B Higgins

Abstract

To determine the capability of high speed computed transmission tomography to quantitate regional wall thickening dynamics over a wide range of physiologic states, left ventricular wall thickening was studied in nine anesthetized mongrel dogs in the control state and during separate infusions of dobutamine (10 micrograms/kg per min) and phenylephrine (25 micrograms/kg per min). After an intravenous bolus of contrast medium the heart was imaged from base to apex with serial transverse images in eight short-axis cine computed tomographic planes. In each dog during each experimental condition, 50 ms scans spanning the cardiac cycle were acquired at each anatomic level. Left ventricular epicardial and endocardial boundaries were identified on end-diastolic and end-systolic images at the equatorial left ventricular planes by an objective threshold contour method validated in a series of experiments performed on ex vivo anatomic specimens. End-diastolic and end-systolic frames were automatically realigned by superposition of epicardial centers of gravity and then rotated using a cross correlation function. The left ventricular wall thickness was measured manually at 16 points around the circumference by two independent observers. For...Continue Reading

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Citations

Jan 1, 1987·International Journal of Cardiac Imaging·M J Lipton
Jan 1, 1987·Cardiovascular and Interventional Radiology·M J Lipton
Apr 1, 1989·Journal of the American College of Cardiology·M J Lipton, J A Rumberger
Oct 1, 1991·Journal of the American College of Cardiology·E RoigB H Brundage
Feb 1, 1996·Journal of the American College of Cardiology·R HoffmannP Hanrath
Sep 15, 2000·Cardiology Clinics·J A Rumberger
Jan 15, 2004·Cardiology Clinics·Lawrence M BoxtMelvin E Clouse
Oct 19, 2004·Journal of the American College of Cardiology·Gabriel YipTheodore Abraham
Aug 14, 2001·São Paulo Medical Journal = Revista Paulista De Medicina·R D CançadoR de C Alves
Jan 10, 2009·International Anesthesiology Clinics·Sherif AfifiAbbas Al-Qamari
Oct 3, 2014·World Journal of Radiology·Robin Man SinghJawahar Lal Mehta

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