Quantitative analysis of allergenic ingredients in eluate extracted from used denture base resin

Journal of Oral Rehabilitation
M MikaiH Fujii

Abstract

Allergenic ingredients extracted from used denture base resin were quantitatively analysed using a gas chromatograph/mass spectrometer and high performance liquid chromatography. Methyl methacrylate (MMA), hydroquinone (HQ), formaldehyde (FMA), benzoyl peroxide (BPO), benzoic acid (BA) and methyl benzoate (MB) were detected in a eluate from all of the dentures, while ethyleneglycol dimethacrylate (DME) was detected in the eluate from 87 dentures in use for <15 years. MMA, HQ, FMA, BPO and MB showed a decrease in correlation to the period of denture use, but continuing to be evident even after 29 years of use. The MMA showed the highest level of elution and a relatively moderate decrease over time. The elution of BA, on the contrary, showed an increase with the period of denture use up to about 10 years and subsequently reached a plateau. Our results indicate that purported allergens exist in the resin base and can be eluted into the oral cavity, even in patients using an old denture for a period of nearly 30 years.

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Citations

Jul 14, 2010·European Journal of Orthodontics·Hilde Molvig KopperudHanne Wellendorf
Sep 17, 2011·Dental Materials : Official Publication of the Academy of Dental Materials·Canan BuralGülsen Bayraktar
May 3, 2011·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Gholamreza DaneshCarsten Lippold
Mar 6, 2015·Dental Materials Journal·Hiroshi MatsuoNobuhiro Takahashi
Oct 18, 2014·International Journal of Occupational Medicine and Environmental Health·Maya LyapinaAngelina Kisselova-Yaneva

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