Quantitative analysis of endosonographic parenchymal echogenicity in patients with chronic pancreatitis

Journal of Gastroenterology and Hepatology
Atsushi IrisawaM S Bhutani

Abstract

The aim of the study was to develop a method of quantitation of endoscopic ultrasonography (EUS) changes of chronic pancreatitis (CP). Twenty-three patients with chronic pancreatitis by EUS were compared with nine normal subjects. Hyperechogenicity was evaluated as the size of the hyperechoic area that was over a threshold echogenicity level. Mean echo density was expressed using the average gray-scale value within the region of interest. The quantitative data were compared with the diagnosis using conventional EUS criteria. The size of the hyperechoic area over the threshold level was 0.86 +/- 0.67 mm2 (mean +/- SD) in the normal pancreas using EUS criteria. In chronic pancreatitis, the size of the hyperechoic area was 7.28 +/- 2.98 mm2 in patients with mild CP, 18.12 +/- 2.56 mm2 in patients with moderate CP, and 18.02 +/- 10.81 mm2 in patients with severe CP, respectively. These changes in hyperechoic size area were statistically significant in all patients having mild to severe CP when compared with normal controls. Computer analysis of EUS images may provide objective information for the diagnosis of CP and may be useful in quantitating the severity of disease and overcoming interobserver variability in analyzing individua...Continue Reading

References

Sep 1, 1985·Journal of Clinical Ultrasound : JCU·K ItohT Konishi
Jul 1, 1984·Gut·M Sarner, P B Cotton
Jan 1, 1995·Ultrasound in Medicine & Biology·B Hamm, F Fobbe
Nov 1, 1993·Pancreas·G Klöppel, B Maillet
Jul 1, 1993·Gastrointestinal Endoscopy·G C SturnioloR H Riddell
Dec 9, 1998·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Y MoritaA Hashimoto
Feb 27, 1999·Gastrointestinal Endoscopy·R H Hawes
Jul 10, 1999·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·M S Bhutani
Sep 30, 1999·Gastroenterology Clinics of North America·M S Bhutani

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Citations

Jan 24, 2007·Journal of Gastroenterology·Atsushi IrisawaMasaru Koizumi
Dec 21, 2010·Current Gastroenterology Reports·Tyler Stevens
Aug 12, 2005·Current Opinion in Gastroenterology·Richard S Kwon, William R Brugge
Aug 12, 2005·Current Opinion in Gastroenterology·Matthew J DiMagno, Eugene P DiMagno
Jun 18, 2010·World Journal of Gastroenterology : WJG·Tyler Stevens, Mansour A Parsi
Oct 31, 2009·Journal of Gastroenterology·Jin Kan SaiSumio Watanabe
Oct 2, 2013·Gastrointestinal Endoscopy Clinics of North America·Tyler Stevens
Apr 9, 2015·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·L Abbigail GrangerLorrie Gaschen
Jul 6, 2010·Gastrointestinal Endoscopy·Timothy B Gardner, Michael J Levy
Apr 29, 2008·Gastrointestinal Endoscopy·Manoop S Bhutani
Jul 22, 2014·Journal of Clinical Ultrasound : JCU·Hyeon Tae JeongMyeong-Jin Kim
Dec 3, 2020·Diagnostics·Yusuke TakasakiHiroyuki Isayama
Nov 10, 2021·Journal of Veterinary Internal Medicine·Harry CridgeJörg M Steiner

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