Quantitative analysis of intrathoracic airway trees: methods and validation

Information Processing in Medical Imaging : Proceedings of the ... Conference
Kálmán PalágyiMilan Sonka

Abstract

A method for quantitative assessment of tree structures is reported allowing evaluation of airway or vascular tree morphology and its associated function. Our skeletonization and branch-point identification method provides a basis for tree quantification or tree matching, tree-branch diameter measurement in any orientation, and labeling individual branch segments. All main components of our method were specifically developed to deal with imaging artifacts typically present in volumetric medical image data. The proposed method has been tested in 343 computer phantom instances subjected to changes of its orientation as well as in a repeatedly CT-scanned rubber plastic phantom width sub-voxel accuracy and high reproducibility. Application to 35 human in vivo trees yielded reliable and well-positioned centerlines and branch-points.

Citations

Oct 28, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Daniel R EinsteinRichard A Corley
Feb 5, 2010·American Journal of Respiratory and Critical Care Medicine·Connie C W HsiaUNKNOWN ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure

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