Quantitative aspects of metabolic organization: a discussion of concepts

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
S A Kooijman

Abstract

Metabolic organization of individual organisms follows simple quantitative rules that can be understood from basic physical chemical principles. Dynamic energy budget (DEB) theory identifies these rules, which quantify how individuals acquire and use energy and nutrients. The theory provides constraints on the metabolic organization of subcellular processes. Together with rules for interaction between individuals, it also provides a basis to understand population and ecosystem dynamics. The theory, therefore, links various levels of biological organization. It applies to all species of organisms and offers explanations for body-size scaling relationships of natural history parameters that are otherwise difficult to understand. A considerable number of popular empirical models turn out to be special cases of the DEB model, or very close numerical approximations. Strong and weak homeostasis and the partitionability of reserve kinetics are cornerstones of the theory and essential for understanding the evolution of metabolic organization.

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Citations

May 10, 2011·Oecologia·Peter J EdmundsErik B Muller
Jun 2, 2006·Ecotoxicology·Tjalling JagerSebastiaan A L M Kooijman
Jul 28, 2009·Ecotoxicology·Erik B MullerHeather A Berkley
Nov 28, 2012·Ecotoxicology·Tjalling JagerVirginie Ducrot
May 17, 2005·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Marc BaillieulRonny Blust
Oct 22, 2013·Ecotoxicology and Environmental Safety·Junho JeonJuliane Hollender
Feb 11, 2004·Water Research·Bernd W BrandtSebastiaan A L M Kooijman
Aug 12, 2003·Bulletin of Mathematical Biology·Konstadia Lika, Sebastiaan A L M Kooijman
Oct 9, 2001·Trends in Biochemical Sciences·R J Ellis
May 22, 2007·SAR and QSAR in Environmental Research·S A L M KooijmanB Van Hattum
Mar 12, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Tânia SousaS A L M Kooijman
Oct 6, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Tânia SousaS A L M Kooijman
Feb 23, 2007·Biological Reviews of the Cambridge Philosophical Society·S A L M Kooijman, T A Troost
Nov 20, 2008·Biological Reviews of the Cambridge Philosophical Society·S A L M KooijmanT Jager
Dec 4, 2009·PLoS Computational Biology·Albert A de GraafBen van Ommen
Sep 23, 2009·Ecotoxicology·Tjalling JagerSebastiaan A L M Kooijman
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