Quantitative assessment of systolic left ventricular function with speckle-tracking echocardiography in adult patients with repaired aortic coarctation

The International Journal of Cardiovascular Imaging
Myrthe E MentingJolien W Roos-Hesselink

Abstract

Despite successful aortic coarctation (CoA) repair, systemic hypertension often recurs which may influence left ventricular (LV) function. We aimed to detect early LV dysfunction using LV global longitudinal strain (GLS) in adults with repaired CoA, and to identify associations with patient and echocardiographic characteristics. In this cross-sectional study, patients with repaired CoA and healthy controls were recruited prospectively. All subjects underwent echocardiography, ECG and blood sampling within 1 day. With speckle-tracking echocardiography, we assessed LV GLS on the apical four-, three- and two-chamber views. We included 150 subjects: 75 patients (57 % male, age 33.4 ± 12.8 years, age at repair 2.5 [IQR: 0.1-11.1] years) and 75 healthy controls of similar sex and age. LV GLS was lower in patients than in controls (-17.1 ± 2.3 vs. -20.2 ± 1.6 %, P < 0.001). Eighty percent of the patients had a normal LV ejection fraction, but GLS was still lower than in controls (P < 0.001). In patients, GLS correlated with systolic and diastolic blood pressure (r = 0.32, P = 0.009; r = 0.31, P = 0.009), QRS duration (r = 0.34, P = 0.005), left atrial dimension (r = 0.27, P = 0.029), LV mass (r = 0.30, P = 0.014) and LV ejection fract...Continue Reading

References

May 1, 1987·British Heart Journal·P PresbiteroA Brusca
Dec 12, 2001·Journal of the American College of Cardiology·P VerdecchiaUNKNOWN MAVI (MAssa Ventricolare sinistra nell'Ipertensione) Study Group
Feb 28, 2002·The American Journal of Cardiology·Olga H Toro-SalazarJames H Moller
Dec 10, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Helmut BaumgartnerUNKNOWN EAE/ASE
Mar 27, 2010·Journal of the American College of Cardiology·Charalambos VlachopoulosChristodoulos Stefanadis
Apr 9, 2010·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrizio LancellottiUNKNOWN European Association of Echocardiography
May 4, 2010·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrizio LancellottiUNKNOWN European Association of Echocardiography
Aug 31, 2010·European Heart Journal·Helmut BaumgartnerUNKNOWN ESC Committee for Practice Guidelines (CPG)
Jan 5, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Sergio MondilloUNKNOWN Echocardiography Study Group Of The Italian Society Of Cardiology (Rome, Italy)
Mar 25, 2011·International Journal of Cardiology·Antonia C MoutafiConstantinos H Davos
May 18, 2011·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Hirokazu MiyoshiTakashi Oki
Jun 8, 2012·Circulation·Idan RoifmanAriane J Marelli
Sep 18, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Niels RisumJoseph Kisslo
Dec 12, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Teerapat YingchoncharoenThomas H Marwick
Sep 17, 2013·The American Journal of Cardiology·Kristin C LombardiConstance G Weismann
Oct 15, 2013·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Salvatore P CostaRobert T Palac
Jan 16, 2015·European Heart Journal Cardiovascular Imaging·Vivian Wing-yi Li, Yiu-fai Cheung
Jan 28, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jens-Uwe VoigtLuigi Paolo Badano
Mar 10, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Yasufumi NagataYutaka Otsuji

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Citations

Dec 1, 2017·The International Journal of Cardiovascular Imaging·Leonel Avendaño-PérezNilda Espinola-Zavaleta
Dec 7, 2017·Pediatric Cardiology·Elles J DijkemaHeynric B Grotenhuis
Dec 2, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Felix Sebastian OberhofferMohamed Abd El Rahman
Feb 26, 2020·Pediatric Cardiology·Fabien LabombardaFarzin Beygui
Mar 21, 2017·The International Journal of Cardiovascular Imaging·Johan H C ReiberNico R L Vande Veire
Nov 25, 2020·Echocardiography·Natalia Freitas de Deus Vale AragãoSimone Rolim Fernandes Fontes Pedra
Sep 26, 2020·Pediatric Cardiology·Fabien LabombardaFarzin Beygui
Dec 29, 2020·American Journal of Medical Genetics. Part a·Gerarda CappuccioNicola Brunetti-Pierri
Mar 15, 2021·Echocardiography·Biagio Castaldi, Giovanni Di Salvo

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