Quantitative Assessment of the Effects of Compression on Deep Learning in Digital Pathology Image Analysis.

JCO Clinical Cancer Informatics
Yijiang ChenAnant Madabhushi

Abstract

Deep learning (DL), a class of approaches involving self-learned discriminative features, is increasingly being applied to digital pathology (DP) images for tasks such as disease identification and segmentation of tissue primitives (eg, nuclei, glands, lymphocytes). One application of DP is in telepathology, which involves digitally transmitting DP slides over the Internet for secondary diagnosis by an expert at a remote location. Unfortunately, the places benefiting most from telepathology often have poor Internet quality, resulting in prohibitive transmission times of DP images. Image compression may help, but the degree to which image compression affects performance of DL algorithms has been largely unexplored. We investigated the effects of image compression on the performance of DL strategies in the context of 3 representative use cases involving segmentation of nuclei (n = 137), segmentation of lymph node metastasis (n = 380), and lymphocyte detection (n = 100). For each use case, test images at various levels of compression (JPEG compression quality score ranging from 1-100 and JPEG2000 compression peak signal-to-noise ratio ranging from 18-100 dB) were evaluated by a DL classifier. Performance metrics including F1 score...Continue Reading

References

Jun 26, 2009·Human Pathology·Ronald S WeinsteinJohn R Gilbertson
Dec 15, 2010·IEEE Transactions on Visualization and Computer Graphics·Quentin MérigotLeonidas Guibas
Dec 1, 2015·Archives of Pathology & Laboratory Medicine·Julien Meyer, Guy Paré
Jul 18, 2016·Medical Image Analysis·Anant Madabhushi, George Lee
Aug 27, 2016·Journal of Pathology Informatics·Andrew Janowczyk, Anant Madabhushi
Apr 21, 2017·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Mira ValkonenPekka Ruusuvuori
Dec 14, 2017·JAMA : the Journal of the American Medical Association·Babak Ehteshami BejnordiRui Venâncio
Jun 19, 2018·Journal of Pathology Informatics·Henrik HelinJorma Isola
Jul 12, 2018·IEEE Transactions on Medical Imaging·Miguel Hernandez-CabroneroJoan Serra-Sagrista
Oct 12, 2018·Archives of Pathology & Laboratory Medicine·Mark D ZarellaDouglas J Hartman

❮ Previous
Next ❯

Citations

Jun 26, 2021·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Birgid Schömig-MarkiefkaYuri Tolkach

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

JPEG
JPEG2000
NVidia Titan X
OpenJPEG

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society
D J ForanI Marsic
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Robina Ashraf, Muhammad Akbar
© 2021 Meta ULC. All rights reserved