Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Li SuSriniVas R Sadda

Abstract

To study the retinal capillary microvasculature and the choriocapillaris (CC) in myopic eyes using swept-source optical coherence tomography angiography (SS-OCTA). Patients with high myopia (≥ - 6D; axial length ≥ 26.5 mm), moderate myopia (≥ - 3D, < - 6D), and age-matched healthy subjects presenting to the Shanghai General Hospital and Doheny-UCLA Eye Centers were enrolled in this prospective, multicenter study. Any subjects with evidence of macular abnormalities suggestive of pathologic myopia were excluded. SS-OCTA at both sites was performed using a Zeiss PLEX Elite instrument with a 6 × 6 mm scan pattern centered on the fovea. Two repeated volume scans were acquired for image averaging. The instrument pre-defined en face slab of the superficial and deep retinal capillary microvasculature was used to isolate and display the superficial and deep retinal capillaries. A slab spanning from 21 to 31 μm deep to the RPE fit line was used to isolate and display the CC. The OCTA images were exported for averaging using Image J. Littmann's method and the Bennett formula were applied to adjust for the impact of magnification in the high and moderate myopia groups. The resultant images were then binarized. Though projection artifact re...Continue Reading

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Citations

Sep 4, 2020·Translational Vision Science & Technology·Li SuIrena Tsui
Oct 14, 2020·Eye·Federico CorviSrinivas R Sadda
Dec 16, 2020·Current Eye Research·Federico CorviSriniVas R Sadda
Jan 5, 2021·Investigative Ophthalmology & Visual Science·Hao WuXiangtian Zhou
Dec 22, 2020·Translational Vision Science & Technology·Li SuIrena Tsui
Oct 17, 2020·Translational Vision Science & Technology·Federico CorviSriniVas R Sadda
Mar 7, 2021·Journal of Clinical Medicine·Jackson ScharfDavid Sarraf
May 8, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Asli Cetinkaya Yaprak, Lutfiye Yaprak
May 19, 2021·Translational Vision Science & Technology·Benjamin R LinIrena Tsui
Aug 4, 2021·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Mei ZhaoAllen My Cheong
Aug 14, 2021·Clinical & Experimental Ophthalmology·Danny Siu-Chun NgTimothy Y Y Lai

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