Quantitative Assessment of Vectorcardiographic Loop Morphology

Journal of Electrocardiology
Golriz SedaghatLarisa G Tereshchenko

Abstract

Vectorcardiography (VCG), developed 100years ago, characterizes clinically important electrophysiological properties of the heart. In this study, VCG QRS loop roundness, planarity, thickness, rotational angle, and dihedral angle were measured in 81 healthy control subjects (39.0±14.2y; 51.8% male; 94% white), and 8 patients with infarct-cardiomyopathy and sustained monomorphic ventricular tachycardia (VT) (68.0±7.8y, 37.5% male). The angle between two consecutive QRS vectors was defined as the rotational angle, while dihedral angle quantified planar alteration over the QRS loop. In VT subjects, planarity index decreased (0.63±0.22 vs. 0.88±0.10; P=0.014), and dihedral angle was significantly more variable (variance of dihedral angle, median (IQR): 897(575-1450) vs. 542(343-773); P=0.029; rMSSD: 47.7±12.7 vs. 35.1±13.1; P=0.027). Abnormal electrophysiological substrate in VT patients is characterized by the appearance of QRS loop folding, likely due to local conduction block. The presence of fragmented QRS complexes on the 12-lead ECG had low sensitivity (31%) for detecting QRS loop folding on the VCG.

References

Mar 1, 1966·Japanese Circulation Journal·K Ohshita
Jan 7, 1982·The New England Journal of Medicine·S T PalmeriG S Wagner
Feb 1, 1993·Japanese Circulation Journal·S HorinakaS Yagi
Jan 15, 2005·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Jean-Philippe CoudercArthur J Moss
Jan 31, 2006·The American Journal of Cardiology·Juha S PerkiömäkiHeikki V Huikuri
Oct 24, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mithilesh Kumar DasDouglas P Zipes
Nov 1, 2007·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Fabrice ExtramianaAntoine Leenhardt

❮ Previous
Next ❯

Citations

Jan 11, 2017·Journal of Electrocardiology·Muammar M KabirLarisa G Tereshchenko
Apr 6, 2019·Acta Cardiologica·Christian Brohet

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.