Quantitative characterization of turbidity by radiative transfer based reflectance imaging

Biomedical Optics Express
Peng TianXin-Hua Hu

Abstract

A new and noncontact approach of multispectral reflectance imaging has been developed to inversely determine the absorption coefficient of μ a , the scattering coefficient of μs and the anisotropy factor g of a turbid target from one measured reflectance image. The incident beam was profiled with a diffuse reflectance standard for deriving both measured and calculated reflectance images. A GPU implemented Monte Carlo code was developed to determine the parameters with a conjugate gradient descent algorithm and the existence of unique solutions was shown. We noninvasively determined embedded region thickness in heterogeneous targets and estimated in vivo optical parameters of nevi from 4 patients between 500 and 950nm for melanoma diagnosis to demonstrate the potentials of quantitative reflectance imaging.

References

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Jun 30, 2005·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Huafeng DingXin-Hua Hu
Sep 8, 2007·Medical Physics·Cheng ChenXin-Hua Hu
May 10, 2008·Journal of Biomedical Optics·Darren RoblyerAnn M Gillenwater
Jan 12, 2004·Optics Express·Bujin GuoA Cho
Nov 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles M BalchVernon K Sondak
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Dec 24, 2011·Journal of Biomedical Optics·Sheldon F BishJames W Tunnell
Jan 21, 2015·Journal of Biophotonics·Pejhman GhassemiJessica C Ramella-Roman
Aug 27, 2015·Biomedical Optics Express·Hui Min Leung, Arthur F Gmitro

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