Quantitative Comparison of Retinal Vascular Features in Optical Coherence Tomography Angiography Images From Three Different Devices

Ophthalmic Surgery, Lasers & Imaging Retina
Neha AnegondiAbhijit Sinha Roy

Abstract

To compare optical coherence tomography angiography (OCTA) images from three different devices. This was a prospective, observational, cross-sectional study. All eyes (n = 24) were imaged thrice each time with swept-source OCT (DRI OCT Triton Plus; Topcon, Tokyo, Japan), spectral-domain OCTA (AngioVue; Optovue, Fremont, CA), and SD-OCT Angioplex (Cirrus HD-OCT 5000; Carl Zeiss Meditec, Jena, Germany). Outcome measures were foveal avascular zone (FAZ) area, vessel density, spacing between large vessels (SLV), and spacing between small vessels (SSV). They were calculated using local fractal analyses and Frangi filter. The vascular parameters showed good to excellent repeatability (intraclass coefficient > 0.8) in the three devices. The FAZ area (P = .3) and vessel density of the superficial layer (P = .8) were similar between the devices. In the deep layer, vessel density was significantly higher (P = .02) with Angio-Vue images compared to those acquired using the other devices. However, SLV was significantly higher (P < .05) and SSV was significantly lower (P < .05) on Angioplex scans compared to other devices. Vessel parameters were significantly altered in Frangi-filtered images as compared to nonfiltered images. Vessel densit...Continue Reading

References

Oct 3, 2015·Retina·Richard F SpaideNadia K Waheed
Nov 26, 2015·Ophthalmic Surgery, Lasers & Imaging Retina·Alexander H de Castro-AbegerCaroline R Baumal
Jan 6, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Jason T SzelogJay S Duker
Jan 25, 2016·Investigative Ophthalmology & Visual Science·Santosh G K GaddeAbhijit Sinha Roy
Jan 30, 2016·The British Journal of Ophthalmology·Marcus AngMark R Wilkins
Mar 31, 2016·Developments in Ophthalmology·Caroline R Baumal
Jul 15, 2016·Investigative Ophthalmology & Visual Science·Eliana CostanzoEric H Souied
Jul 30, 2016·Investigative Ophthalmology & Visual Science·Devanshi BhanushaliAbhijit Sinha Roy
Oct 21, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Rohan ChawlaRajpal Vohra
Nov 8, 2016·Investigative Ophthalmology & Visual Science·Rajesh S KumarAbhijit Sinha Roy
Apr 15, 2015·International Journal of Retina and Vitreous·Talisa E de CarloJay S Duker
Jan 16, 2017·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Jiaxian GuoXiaodong Sun
Feb 13, 2017·Archivos de la Sociedad Española de Oftalmología·R Torrecillas-PicazoA Duch-Samper
Mar 16, 2017·International Journal of Retina and Vitreous·Jose Mauricio Botto de Barros GarciaMarcos Avila
Apr 24, 2017·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Jost L LauermannFlorian Alten
May 11, 2017·PloS One·Marion R MunkMartin S Zinkernagel
May 13, 2017·Ophthalmic Surgery, Lasers & Imaging Retina·Mayss Al-SheikhSriniVas R Sadda

❮ Previous
Next ❯

Citations

Jan 22, 2020·Experimental Biology and Medicine·Xincheng YaoDevrim Toslak
Dec 21, 2018·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·N MihailovicM Alnawaiseh
Jul 25, 2019·Translational Vision Science & Technology·Omer AharonyYair Zimmer
Apr 4, 2020·Vestnik oftalmologii·N S SemenovaV S Akopyan
Dec 19, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Bryce W PolascikSharon Fekrat
Jan 8, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kimberly SpoonerAndrew A Chang

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging technique

Software Mentioned

AngioVue
MedCalc

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.