Quantitative Comparison of Swept-Source and Spectral-Domain OCT Angiography in Healthy Eyes

Ophthalmic Surgery, Lasers & Imaging Retina
Mayss Al-SheikhSrinivas R Sadda

Abstract

To compare macular vessel density (VD) and foveal avascular zone (FAZ) area in healthy individuals using two different optical coherence tomography angiography (OCTA) devices. In this prospective, comparative study, 25 eyes of 14 healthy subjects underwent fovea-centered 3 mm × 3 mm OCTA-imaging using the Triton (Topcon, Tokyo, Japan) and RS-3000 (Nidek, Gamagori, Japan) OCTA devices. Superficial and deep retinal layers (SRL/DRL) and FAZ were manually graded after threshold standardization to determine macular VD and area of the FAZ. The mean difference in the VD between the two devices was 0.105 and 0.096, and the coefficient of variation (CV) was 19.59% and 16.90% for the SRL and DRL, respectively. After skeletonization of vessels to remove variation related to vessel width, the mean difference was 0.174 mm-1 and 0.516 mm-1, and the CV was 3.49% and 1.07% for SRL and DRL, respectively. The mean difference of FAZ area was 0.001 mm2 and 0.010 mm2 in the SRL and DRL, respectively, and the CV was 2.17% and 5.74% for the SRL and DRL, respectively. Macular VD using skeletonized mapping and FAZ area in SRL and DRL were statistically similar between the two devices, demonstrating a possible comparison of quantitative values between d...Continue Reading

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Citations

Jul 7, 2018·PloS One·Ikrame DoumaPhilippe Denis
Jul 19, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Neha AnegondiAbhijit Sinha Roy
Mar 13, 2019·European Journal of Ophthalmology·José Ignacio Fernández-VigoJosé Ángel Fernández-Vigo
May 18, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Ilkay Kilic MuftuogluWilliam R Freeman
Sep 2, 2020·Ocular Immunology and Inflammation·Hyun Goo KangChristopher Seungkyu Lee
Oct 20, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Malvika AryaNadia K Waheed
Jul 10, 2019·Current Eye Research·Hayati YilmazSumeyye Burcu Elpeze
May 6, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Emily S LevineNadia K Waheed
Mar 8, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Li SuSriniVas R Sadda
Sep 26, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yifan LuJohn B Miller

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Software Mentioned

Power
MedCalc
OCTA
SPSS

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