Quantitative correlation between light depolarization and transport albedo of various porcine tissues

Journal of Biomedical Optics
Sanaz AlaliI Alex Vitkin

Abstract

We present a quantitative study of depolarization in biological tissues and correlate it with measured optical properties (reduced scattering and absorption coefficients). Polarized light imaging was used to examine optically thick samples of both isotropic (liver, kidney cortex, and brain) and anisotropic (cardiac muscle, loin muscle, and tendon) pig tissues in transmission and reflection geometries. Depolarization (total, linear, and circular), as derived from polar decomposition of the measured tissue Mueller matrix, was shown to be related to the measured optical properties. We observed that depolarization increases with the transport albedo for isotropic and anisotropic tissues, independent of measurement geometry. For anisotropic tissues, depolarization was higher compared to isotropic tissues of similar transport albedo, indicating birefringence-caused depolarization effects. For tissues with large transport albedos (greater than ~0.97), backscattering geometry was preferred over transmission due to its greater retention of light polarization; this was not the case for tissues with lower transport albedo. Preferential preservation of linearly polarized light over circularly polarized light was seen in all tissue types an...Continue Reading

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Citations

Oct 10, 2013·Optics Letters·Sanaz AlaliI Alex Vitkin
Oct 17, 2014·Applied Optics·Mahesh Kumar SwamiPradeep Kumar Gupta
Sep 24, 2015·Journal of Biophotonics·Iftikhar AhmadAlex Vitkin
Jun 16, 2015·Photodiagnosis and Photodynamic Therapy·Iftikhar AhmadMasroor Ikram
Dec 4, 2013·Biomedical Optics Express·Ji QiDaniel S Elson
Jun 3, 2016·Lasers in Surgery and Medicine·Vivek Krishna Nagarajan, Bing Yu
May 14, 2016·Scientific Reports·Ji Qi, Daniel S Elson
Apr 29, 2016·Journal of Biomedical Optics·Valery V Tuchin
Mar 10, 2019·Journal of Biomedical Optics·Joseph Chue-SangJessica C Ramella-Roman
Apr 15, 2015·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·C M MacdonaldI V Meglinski
May 4, 2017·Journal of Biophotonics·Ji Qi, Daniel S Elson
Apr 23, 2020·Photodiagnosis and Photodynamic Therapy·Muhammad Sajid YousafMasroor Ikram

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