PMID: 2492777Jan 1, 1989Paper

Quantitative determination of circulating antigens in human schistosomiasis mansoni using an indirect hemagglutination assay

The American Journal of Tropical Medicine and Hygiene
A M DeelderA M Polderman

Abstract

In serum and urine specimens collected from a group of Schistosoma mansoni infected individuals from Makundju, Zaire, the schistosome circulating anodic antigen (CAA) and the circulating cathodic antigen (CCA) were quantitatively determined using an indirect hemagglutination reaction with sheep erythrocytes sensitized with mouse IgM monoclonal antibodies directed against these circulating antigens. Levels of CAA in serum (up to 5 ng/ml) and CCA in serum and urine (up to 50 ng/ml) were strongly correlated with egg excretion and with each other. No correlation was found between egg excretion and antibody levels against the circulating antigens. Antigen was detectable only in patients excreting greater than 500 eggs per gram of feces.

Citations

Nov 1, 1990·Transactions of the Royal Society of Tropical Medicine and Hygiene·N de JongeA M Deelder
Jan 1, 1990·Scandinavian Journal of Infectious Diseases·Y T PitkänenE Linder
Feb 25, 1999·Memórias do Instituto Oswaldo Cruz·Y Pereira e SilvaA Rabello
Apr 18, 2000·Infection and Immunity·A Ribeiro de JesusE M Carvalho
Jan 22, 2003·Tropical Medicine & International Health : TM & IH·Yong-Long LiAndreas Ruppel
Mar 12, 2015·The Cochrane Database of Systematic Reviews·Eleanor A OchodoMariska M G Leeflang
Dec 23, 2016·PLoS Neglected Tropical Diseases·Kenneth R HawkinsTala de Los Santos
Mar 14, 2014·International Journal of STD & AIDS·Eyrun F KjetlandMyra Taylor
Mar 1, 1995·Journal of Travel Medicine·M Corachán
Nov 1, 1991·Transactions of the Royal Society of Tropical Medicine and Hygiene·N De JongeA M Deelder
Mar 8, 2013·PLoS Neglected Tropical Diseases·Rafaella GrenfellPaulo Marcos Zech Coelho
Jun 14, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lucheri EfraimJennifer A Downs
Feb 21, 2014·Revista Da Sociedade Brasileira De Medicina Tropical·Luciana Inácia GomesAna Rabello
Sep 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·N de JongeA M Deelder
Mar 23, 2021·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Enas A El Saftawy
Jan 1, 2004·Trends in Parasitology·Michael J DoenhoffJoanne V Hamilton

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