Quantitative heel ultrasound in assessment of bone structure in renal transplant recipients

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
A MondryB Grabensee

Abstract

Many patients with advanced renal disease have osteopenia or even osteoporosis by the definition of the World Health Organization based on bone mineral density (BMD). Dual-energy X-ray absorptiometry (DXA), the standard method to assess BMD, is not always available. Quantitative heel ultrasound (QUS) is an inexpensive, mobile, and radiation-free diagnostic alternative, yet few data address this method's usefulness in patients with renal disease. The present study assessed the value of QUS in detecting changes in bone structure in renal transplant recipients compared with DXA. In a cross-sectional analysis, 50 patients (29 women) with a mean age of 50 +/- 13 years, mean time since transplantation of 60 months (range, 1 to 205 months), and stable renal allograft function were studied. BMD was quantified by DXA of the hip and spine. QUS of the left heel measured broadband ultrasound attenuation (BUA) and speed of sound (SOS). Stiffness index (SI) was calculated as SI = (0.67 * BUA + 0.28 * SOS) - 420. DXA measurements established the diagnoses of osteopenia and osteoporosis in 49% and 22% of the patients, respectively. Femoral neck BMD and QUS parameters showed good correlation (r = 0.638; P < 0.001). Sensitivities of BUA, SOS, an...Continue Reading

References

Jul 1, 1994·Calcified Tissue International·C C GlüerH K Genant
Aug 1, 1994·Calcified Tissue International·D HansP J Meunier
Jan 1, 1997·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E W GreggJ A Cauley
Jul 17, 1998·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R Strelitzki, J G Truscott
Aug 26, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M W TaalT Masud
Dec 14, 1999·Calcified Tissue International·A RapadoI García

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Citations

Jul 3, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Cornelis G ter MeulenAndries J Hoitsma
Apr 30, 2008·Rheumatology International·Alia M AtallahMohamed A Ghoneim
Sep 17, 2013·Clinical Transplantation·Athanasios ChristoforidisFotios Papachristou
May 27, 2014·Journal of Bone and Mineral Metabolism·Chrysa GkogkaFotios Papachristou
May 6, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D KovacF A Bren
Jan 10, 2006·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J W R Braga JúniorA B Carvalho

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