Quantitative magnetic resonance angiography of the cerebrovasculature in physiologic and pathologic states

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Stafford A ConwayCamilo R Gomez

Abstract

In the past, clinical decisions regarding treatment of neurovascular disorders leading to ischemia have been guided by the percentage of stenosis of the vessel in question. However, such an approach assumes a predictable and stable relationship between the percentage of stenosis and the degree of flow reduction it causes. Historically, this type of relationship has been difficult to document. Thus, a method for noninvasively measuring the absolute flow of specific cerebral arteries is of potential practical value. We set to quantify the mean blood flow (Qm, in mL/min) in the cerebral arteries using quantitative magnetic resonance angiography (QMRA), and to compare the findings in normal vessels with those found in vessels considered pathologically narrowed. Specific vascular segments were identified, studied, and the results entered into a database. Statistical analyses of the measurements were carried out using StatPlus for Microsoft Excel. It involved comparing of the Qm found in specific vessels, as well as those found in normal and abnormal vessels, using analysis of variance (ANOVA). The abnormal vessels were selected from specifically identified magnetic resonance angiography (MRA) studies. A total of 57 patients, 26 men ...Continue Reading

References

Aug 10, 2000·Magnetic Resonance Imaging·M ZhaoM E Clark
Oct 4, 2003·Stroke; a Journal of Cerebral Circulation·David J BlackerEelco F M Wijdicks
May 14, 2005·Stroke; a Journal of Cerebral Circulation·Sepideh Amin-HanjaniFady T Charbel
Jan 25, 2006·Circulation·Scott E KasnerUNKNOWN Warfarin Aspirin Symptomatic Intracranial Disease Trial Investigators

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Citations

Jan 15, 2009·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Wilma SchierlingThomas Schmitz-Rixen
Nov 26, 2009·Annals of Neurology·David S Liebeskind
Oct 9, 2021·AJNR. American Journal of Neuroradiology·Y TakedaN Saito

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