PMID: 11343947May 10, 2001Paper

Quantitative measurement of endothelium derived nitric oxide production of the internal mammary artery bypass graft during extracorporeal circulation

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
F TarrI Tomcsányi

Abstract

This study was undertaken to determine the extent of endothelium derived nitric oxide (EDNO) production of the internal mammary artery (IMA) bypass graft and of the native coronary circulation by measuring its stable metabolite (NO2: nitrite) in different sampling sites: internal mammary free cut end flow, in the coronary sinus prior and after anastomosis completion, and to compare them to the nitrite level of the normal plasma. Nitrite level was determined with fluoroscopy using 4 hydroxycoumarin nitrozation in 50 consecutive patient undergoing onpump myocardial revascularization. Nitrite levels in the normal plasma were found to be 31.2 micromol. Nitrite level in systemic and coronary circulation after total heparinization, prior to extracorporeal circulation (ECC) was found to be 60.8 micromol (lower quartile /l.q./: 46.6 micromol, upper quartile /u.q./: 70.0 micromol,) and 58.3 micromol,(l.q.:47.8 micromol, u.q.:70.0 micromol) respectively, and of the IMA bypass graft free cut end flow was 54.4 micromol,(l.q.:42.0 micromol, u.q.:66.8 micromol) while in the coronary sinus, after completion the IMA anastomosis, it was 45.71 micromol (l.q.: 35.0 micromol, u.q.: 55.0 micromol), (all geometric mean). Total heparinization enhance...Continue Reading

References

Aug 1, 1991·Cardiovascular Research·Z BenyóA G Kovách
Sep 1, 1990·The Annals of Thoracic Surgery·R KoikeA Takeuchi
Jun 1, 1989·The Thoracic and Cardiovascular Surgeon·K H LehmannM Turina
Aug 25, 1988·The New England Journal of Medicine·T F LüscherE Weber
Dec 1, 1986·Analytical Chemistry·T OhtaS Takitani
Apr 26, 1984·The New England Journal of Medicine·G A FitzGeraldA R Brash
May 22, 1998·The Annals of Thoracic Surgery·P J PearsonH V Schaff
Nov 4, 1998·The Annals of Thoracic Surgery·P C KouretasR L Hannan

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Citations

Apr 20, 2007·Journal of Cardiovascular Medicine·Guglielmo BernardiDavide Zanuttini
Apr 20, 2007·Journal of Cardiovascular Medicine·Ottavio AlfieriAlessandro Castiglioni

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