Quantitative Microbial Risk Assessment for Workers Exposed to Bioaerosol in Wastewater Treatment Plants Aimed at the Choice and Setup of Safety Measures

International Journal of Environmental Research and Public Health
A CarducciMarco Verani

Abstract

Biological risk assessment in occupational settings currently is based on either qualitative or semiquantitative analysis. In this study, a quantitative microbial risk assessment (QMRA) has been applied to estimate the human adenovirus (HAdV) health risk due to bioaerosol exposure in a wastewater treatment plant (WWTP). A stochastic QMRA model was developed considering HAdV as the index pathogen, using its concentrations in different areas and published dose⁻response relationship for inhalation. A sensitivity analysis was employed to examine the impact of input parameters on health risk. The QMRA estimated a higher average risk in sewage influent and biological oxidation tanks (15.64% and 12.73% for an exposure of 3 min). Sensitivity analysis indicated HAdV concentration as a predominant factor in the estimated risk. QMRA results were used to calculate the exposure limits considering four different risk levels (one illness case per 100, 1.000, 10.000, and 100.000 workers): for 3 min exposures, we obtained 565, 170, 54, and 6 GC/m³ of HAdV. We also calculated the maximum time of exposure for each level for different areas. Our findings can be useful to better define the effectiveness of control measures, which would thus reduce ...Continue Reading

References

Jan 1, 1985·American Journal of Public Health·C S ClarkC R Zeiss
Jun 1, 1996·European Journal of Epidemiology·P Cadilhac, F Roudot-Thoraval
Aug 9, 2001·American Journal of Industrial Medicine·J Thorn, E Kerekes
Jul 12, 2002·The Science of the Total Environment·H D NeumannM Raulf-Heimsoth
Sep 9, 2008·Water Science and Technology : a Journal of the International Association on Water Pollution Research·A CarducciM Verani
Oct 25, 2008·Journal of Environmental Quality·Benjamin D TannerIan L Pepper
Jun 30, 2009·Occupational Medicine·Paolo MontuoriMaria Triassi
Dec 17, 2009·Journal of Water and Health·Duncan Mara, Andrew Sleigh
Jul 13, 2012·Industrial Health·Carmela Romana Natalina CorraoMaria De Giusti
Jul 2, 2014·Environmental Research·Frédéric G MasclauxAnne Oppliger
Aug 12, 2014·Journal of Environmental Sciences (China)·Xuesong GuoLin Li
Jun 20, 2015·Trends in Food Science & Technology·Q L DongP K Malakar
Jun 28, 2016·International Journal of Environmental Research and Public Health·Luigi VimercatiRaffaello Maria Bellino
Jul 23, 2016·International Journal of Environmental Research and Public Health·Annalaura CarducciMarco Verani
Feb 22, 2017·Journal of Food Protection·Hao PangAbani K Pradhan

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Citations

Sep 29, 2019·Water Environment Research : a Research Publication of the Water Environment Federation·Mark W LeChevallierJacqueline MacDonald Gibson
Apr 23, 2020·International Journal of Environmental Research and Public Health·Jamil AhmedJoshua V Garn
Dec 12, 2019·Environmental Monitoring and Assessment·Razieh AnaloueiHamid Reza Safavi
Apr 19, 2019·International Journal of Environmental Research and Public Health·Hamza MbarecheCaroline Duchaine
Apr 2, 2020·Archives of Environmental & Occupational Health·Nai YangXiaoya Ma
Dec 2, 2020·Environmental Pollution·Yunping HanJunxin Liu
Sep 11, 2020·The Science of the Total Environment·Rafael Newton ZanetiRamiro Gonçalves Etchepare
Oct 15, 2020·Environmental Science and Pollution Research International·Cheng YanJun-Ting Wu
Feb 1, 2021·Chemosphere·Sahar GholipourHossein Mirhendi
Mar 7, 2021·The Science of the Total Environment·Mohammad El WaliAndrzej Kraslawski
Aug 8, 2020·The Science of the Total Environment·Masaaki KitajimaJoan B Rose
Oct 27, 2018·The Science of the Total Environment·Marco VeraniAnnalaura Carducci
Jul 4, 2021·Environmental Research·Adebayo Olatunbosun Sojobi, Tarek Zayed
Jul 18, 2021·Environmental Science and Pollution Research International·Rui-Ning WangCheng Yan
Aug 30, 2021·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Susi BurgalassiMarco Verani

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Software Mentioned

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Excel
MathWave Technologies
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