Quantitative Morphological Variation in the Developing Drosophila Wing

G3 : Genes - Genomes - Genetics
Alexis Matamoro-VidalDavid Houle

Abstract

Quantitative genetic variation in morphology is pervasive in all species and is the basis for the evolution of differences among species. The measurement of morphological form in adults is now beginning to be combined with comparable measurements of form during development. Here we compare the shape of the developing wing to its adult form in a holometabolous insect, Drosophila melanogaster We used protein expression patterns to measure shape in the developing precursors of the final adult wing. Three developmental stages were studied: late larval third instar, post-pupariation and in the adult fly. We studied wild-type animals in addition to mutants of two genes (shf and ds) that have known effects on adult wing shape and size. Despite experimental noise related to the difficulty of comparing developing structures, we found consistent differences in wing shape and size at each developmental stage between genotypes. Quantitative comparisons of variation arising at different developmental stages with the variation in the final structure enable us to determine when variation arises, and to generate hypotheses about the causes of that variation. In addition we provide linear rules allowing us to link wing morphology in the larva, ...Continue Reading

References

Dec 13, 2003·BMC Evolutionary Biology·David HouleAshley Carter
Sep 20, 2005·Current Biology : CB·Luis Alberto Baena-LópezAntonio García-Bellido
May 18, 2007·Annual Review of Cell and Developmental Biology·Seth S Blair
Mar 12, 2010·Nature·Isaac Salazar-Ciudad, Jukka Jernvall
Jan 20, 2011·Genes & Development·Yanlan MaoBarry J Thompson
Sep 19, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ricardo MallarinoArhat Abzhanov
Nov 28, 2012·Evolutionary Biology·Eladio J MárquezDavid Houle
Jul 24, 2013·Trends in Ecology & Evolution·Kevin J Parsons, R Craig Albertson
Nov 6, 2013·Genetics·Maria D S NunesAlistair P McGregor
Dec 17, 2014·PloS One·Christine MayerPhilipp Mitteroecker
Jan 27, 2015·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Alexis Matamoro-VidalDavid Houle
Dec 15, 2015·ELife·Boris GuiraoYohanns Bellaïche
Jul 1, 1989·Evolution; International Journal of Organic Evolution·Miriam Leah Zelditch, Christopher Carmichael
Aug 10, 2017·Nature·David HouleThomas F Hansen

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Citations

Jun 18, 2019·Evolution; International Journal of Organic Evolution·Jacqueline L Sztepanacz, David Houle

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Methods Mentioned

BETA
dissection

Software Mentioned

R Core Team
Wings4
R
tpsDig2
Lory
tpsUtil
tpsRelw
SAS
FigShare

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