Quantitative sensory testing in patients with migraine: a systematic review and meta-analysis

Pain
Hadas Nahman-AverbuchRobert C Coghill

Abstract

Quantitative sensory testing (QST) is widely used to assess somatosensory function by application of controlled stimuli across a variety of modalities. The aim of the present meta-analysis is to synthesize QST results across a wide array of studies of patients with migraine to identify the QST parameters that are reliably different between patients with migraine and healthy controls. In addition, we aimed to determine whether such differences vary according to stimulus location. A comprehensive literature search (up to January 2017) was conducted, which included studies comparing QST parameters between patients with migraine and healthy controls. For each QST modality, we calculated up to 3 meta-analyses for combined (combined data from multiple testing locations), local (head and neck), and nonlocal (outside the head or neck) locations. A total of 65 studies were included in the meta-analyses. Lower heat and pressure pain thresholds were observed in patients with migraine compared with healthy controls in the combined locations. Importantly, lower pressure pain threshold in patients with migraine was found in local areas but not in nonlocal areas. In addition, patients with migraine had higher pain ratings to cold suprathresho...Continue Reading

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Citations

Oct 20, 2018·Pain·Hadas Nahman-AverbuchRobert C Coghill
Jan 10, 2019·Pain·Hadas Nahman-AverbuchRobert C Coghill
Nov 7, 2019·Pain·Tibor M SzikszayKerstin Luedtke
Jun 21, 2019·Pain·Kuan-Po Peng, Arne May
Sep 23, 2020·Cephalalgia : an International Journal of Headache·César Fernández-de-Las-PeñasLars Bendtsen
May 8, 2020·The Journal of Headache and Pain·Jacob GeniziBatya Engel-Yeger
Jun 27, 2018·The Journal of Headache and Pain·Kerstin LuedtkeBettina Wollesen
Dec 19, 2019·Cephalalgia : an International Journal of Headache·Dan LevyRuth Defrin
May 19, 2020·Cephalalgia : an International Journal of Headache·Li-Ling Hope PanShuu-Jiun Wang
Oct 14, 2020·Journal of Oral Rehabilitation·Paulo César Rodrigues ContiPeter Svensson
Nov 25, 2020·Headache·Hadas Nahman-AverbuchChristopher D King
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Jul 3, 2021·Journal of Oral Rehabilitation·Yuri M CostaPeter Svensson
Nov 18, 2021·Cephalalgia : an International Journal of Headache·Jan Petter NeverdahlPetter Moe Omland

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