PMID: 6110743Dec 1, 1980Paper

Quantitative structure-activity relationships: the Van't Hoff heats of transfer of resorcinol monoethers from water to n-octanol

The Journal of Pharmacy and Pharmacology
A E BeezerD E Storey

Abstract

The partition coefficients of resorcinol and some resorcinol monoalkyl-ethers from water to n-octanol have been measured as a function of temperature. These data are used to evaluate delta G, delta H and delta S for the solute transfer process. The data suggest direct calorimetric measurement of these parameters should be performed. Correlation with calorimetrically determined 'biological response' will permit a more detailed and precise commentary upon the quantitative structure-activity relationships for these compounds.

References

Oct 1, 1977·Analytical Chemistry·A E BeezerH J Tyrrell
Jun 15, 1979·Experientia·A E BeezerP Willis
Jan 1, 1974·Progress in Medicinal Chemistry·K C James
May 1, 1968·Journal of Medicinal Chemistry·E J LienS M Anderson
Feb 1, 1981·The Journal of Pharmacy and Pharmacology·A E BeezerD E Storey
Feb 1, 1954·Journal of the American Pharmaceutical Association·N A ALLAWALA, S RIEGELMAN

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Citations

Jul 17, 2013·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yun WeiYing Zhang
Sep 1, 1985·Environmental Health Perspectives·J C Dearden
Feb 1, 1981·The Journal of Pharmacy and Pharmacology·A E BeezerD E Storey
Jan 1, 1997·Journal of Receptor and Signal Transduction Research·V Pliska
Feb 3, 2006·The Journal of Physical Chemistry. a·Muftah M BasheerRoberto Rittner

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