Quantitative susceptibility mapping using principles of echo shifting with a train of observations sequence on 1.5T MRI

Magnetic Resonance Imaging
Hirohito KanYuta Shibamoto

Abstract

To evaluate the accuracy of susceptibility estimated from the principles of echo shifting with a train of observations (PRESTO) sequence using a 1.5T MRI system, we conducted experiments on the human brain using the PRESTO sequence and compared our results with the susceptibility obtained from spoiled gradient-recalled echo (GRE) sequence with flow compensation using quantitative susceptibility mapping (QSM) reconstruction. Experiments on the human brain were conducted on 12 healthy volunteers (27±4years) using PRESTO and spoiled GRE sequences on a 1.5T scanner. The PRESTO sequence is an echo-shifted gradient echo sequence that allows high susceptibility sensitivity and rapid acquisition because of TE>TR compared with the spoiled GRE sequence. QSM analysis was performed on the obtained phase images using the iLSQR method. Estimated susceptibility maps were used for region of interest analyses and estimation of line profiles through iron-rich tissue and major vessels. Our results demonstrated that susceptibility maps were accurately estimated, without error, by QSM analysis of PRESTO and spoiled GRE sequences. Acquisition time in the PRESTO sequence was reduced by 43% compared with that in the spoiled GRE sequence. Differences d...Continue Reading

Citations

May 11, 2018·Journal of Magnetic Resonance Imaging : JMRI·Domenico TortoraAndrea Rossi
May 6, 2020·Movement Disorders : Official Journal of the Movement Disorder Society·Yuto UchidaNoriyuki Matsukawa
Feb 26, 2019·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Hirohito KanYuta Shibamoto
May 16, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Yuto UchidaNoriyuki Matsukawa
Dec 7, 2019·AJNR. American Journal of Neuroradiology·N AraiY Shibamoto

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